5-(2,4-DICHLORO-5-FLUOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID

Base Information

• Chemical Name: 5-(2,4-DICHLORO-5-FLUOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID
• CAS No.: 1119299-75-0
• Molecular Formula: C₁₀H₅Cl₂FN₂O₂
• Molecular Weight: 275.066
• Hs Code.: 2933199090
• Mol file: 1119299-75-0.mol

Synonyms:5-(2,4-Dichloro-5-fluorophenyl)-1H-pyrazole-3-carboxylic acid;

Chemical Property of 5-(2,4-DICHLORO-5-FLUOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID

Chemical Property:

• Boiling Point: 513.2±50.0 °C(Predicted)
• PKA: 3.67±0.10(Predicted)
• PSA: 65.98000
• Density: 1.648±0.06 g/cm3(Predicted)
• LogP: 3.22080

Purity/Quality:

97% ^*data from raw suppliers

5-(2,4-Dichloro-5-fluorophenyl)-1h-pyrazole-3-carboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-(2,4-DICHLORO-5-FLUOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID

There total 1 articles about 5-(2,4-DICHLORO-5-FLUOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C11H7Cl2FN2O2 (1119299-64-7) → C10H5Cl2FN2O2 (1119299-75-0)

Guidance literature:

With lithium hydroxide; water; In tetrahydrofuran; methanol; Reflux;

DOI:10.1016/j.bmcl.2008.10.107

Reference yield:

C10H5Cl2FN2O2 (1119299-75-0) + ethanolamine (141-43-5) → C12H10Cl2FN3O2 (1119300-02-5)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2008.10.107

Reference yield:

C10H5Cl2FN2O2 (1119299-75-0) + dimethyl amine (124-40-3) → C12H10Cl2FN3O (1119300-03-6)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2008.10.107

upstream raw materials:

C₁₁H₇Cl₂FN₂O₂

Downstream raw materials:

C₁₂H₁₀Cl₂FN₃O₂

C₁₂H₁₀Cl₂FN₃O

C₁₃H₁₂Cl₂FN₃O

C₁₄H₁₄Cl₂FN₃O₃