(E)-beta,2-Dibromostyrene

Base Information

• Chemical Name: (E)-beta,2-Dibromostyrene
• CAS No.: 430434-57-4
• Molecular Formula: C8H6Br2
• Molecular Weight: 261.944
• DSSTox Substance ID: DTXSID30421264
• Nikkaji Number: J2.543.992I,J920.048G,J2.423.860A
• Mol file: 430434-57-4.mol

Synonyms:1298047-80-9;(E)-beta,2-Dibromostyrene;1-bromo-2-[(E)-2-bromoethenyl]benzene;1-Bromo-2-(2-bromovinyl)benzene;1-bromo-2-(2-bromoethenyl)benzene;430434-57-4;AC1NYJTR;(e)-1-bromo-2-(2-bromovinyl)benzene;bromo(2-bromoethenyl)benzene;[(Z)-2-Bromostyryl] bromide;2-(2-Bromovinyl)phenyl bromide;DTXSID30421264;CS-0265844;EN300-125208

Chemical Property of (E)-beta,2-Dibromostyrene

Chemical Property:

• PSA: 0.00000
• LogP: 3.81470
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 261.88158
• Heavy Atom Count: 10
• Complexity: 120

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C=CBr)Br
• Isomeric SMILES: C1=CC=C(C(=C1)/C=C/Br)Br

Technology Process of (E)-beta,2-Dibromostyrene

There total 6 articles about (E)-beta,2-Dibromostyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

1,1-dibromomethane (74-95-3) + 1-Bromo-2-bromomethyl-benzene (3433-80-5) → (E)-1-bromo-2-(2-bromovinyl) benzene (430434-57-4)

Guidance literature:

1,1-dibromomethane; With sodium hexamethyldisilazane; In tetrahydrofuran; diethyl ether; at -78 ℃; Inert atmosphere; Darkness;

1-Bromo-2-bromomethyl-benzene; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; optical yield given as %de; stereoselective reaction; Inert atmosphere;

Reference yield:

2-bromostyrene (2039-88-5) → 1-bromo-2-[(Z)-2-bromoethenyl]benzene (153140-75-1) + (E)-1-bromo-2-(2-bromovinyl) benzene (430434-57-4)

Guidance literature:

With sodium persulfate; N-Bromosuccinimide; at 100 ℃; for 3h; Overall yield = 33 percent;

Reference yield:

2-bromocinnamic acid (7345-79-1) → 1-bromo-2-[(Z)-2-bromoethenyl]benzene (153140-75-1) + (E)-1-bromo-2-(2-bromovinyl) benzene (430434-57-4)

Guidance literature:

With ammonium bromide; In water; acetonitrile; at 75 ℃; for 1h; Overall yield = 48 %; Electrochemical reaction;

DOI:10.1016/j.cclet.2017.04.030

upstream raw materials:

Bromoform

(bromomethyl)triphenyl phosphonium bromide

ortho-bromobenzaldehyde

1,1-dibromomethane

Downstream raw materials:

2-(2-bromophenyl)pyrazolo[1,5-a]pyridine

(E)-3-(2-bromophenyl)acrylonitrile