<5-Benzyloxy-4-methoxy-2-<4-(triphenylphosphoniomethyl)phenoxy>benzyl>phosphonium-dibromid

Base Information

• Chemical Name: <5-Benzyloxy-4-methoxy-2-<4-(triphenylphosphoniomethyl)phenoxy>benzyl>phosphonium-dibromid
• CAS No.: 118799-10-3
• Molecular Formula: 2Br*C₅₈H₅₀O₃P₂
• Molecular Weight: 1016.79
• Mol file: 118799-10-3.mol

Synonyms:

Chemical Property of <5-Benzyloxy-4-methoxy-2-<4-(triphenylphosphoniomethyl)phenoxy>benzyl>phosphonium-dibromid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <5-Benzyloxy-4-methoxy-2-<4-(triphenylphosphoniomethyl)phenoxy>benzyl>phosphonium-dibromid

There total 12 articles about <5-Benzyloxy-4-methoxy-2-<4-(triphenylphosphoniomethyl)phenoxy>benzyl>phosphonium-dibromid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

5-Benzyloxy-3-(4-brommethylphenoxy)-4-methoxybenzylbromid (118799-09-0) + triphenylphosphine (603-35-0) → <5-Benzyloxy-4-methoxy-2-<4-(triphenylphosphoniomethyl)phenoxy>benzyl>phosphonium-dibromid (118799-10-3)

Guidance literature:

In acetonitrile; for 1h; Heating;

Reference yield:

4-methoxycarbonylphenyl bromide (619-42-1) → <5-Benzyloxy-4-methoxy-2-<4-(triphenylphosphoniomethyl)phenoxy>benzyl>phosphonium-dibromid (118799-10-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 37 percent / K₂CO₃; CuO / pyridine / 48 h / 120 °C

2: 76 percent / K₂CO₃ / acetone / 5 h / Heating

3: 91 percent / LiAlH₄ / tetrahydrofuran

4: 80 percent / PBr₃ / CH₂Cl₂ / 3 h / Ambient temperature

5: 93 percent / acetonitrile / 1 h / Heating

With lithium aluminium tetrahydride; phosphorus tribromide; potassium carbonate; copper(II) oxide; In tetrahydrofuran; pyridine; dichloromethane; acetone; acetonitrile;

Reference yield:

methyl 3,5-dihydroxy-4-methoxybenzoate (24093-81-0) → <5-Benzyloxy-4-methoxy-2-<4-(triphenylphosphoniomethyl)phenoxy>benzyl>phosphonium-dibromid (118799-10-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 37 percent / K₂CO₃; CuO / pyridine / 48 h / 120 °C

2: 76 percent / K₂CO₃ / acetone / 5 h / Heating

3: 91 percent / LiAlH₄ / tetrahydrofuran

4: 80 percent / PBr₃ / CH₂Cl₂ / 3 h / Ambient temperature

5: 93 percent / acetonitrile / 1 h / Heating

With lithium aluminium tetrahydride; phosphorus tribromide; potassium carbonate; copper(II) oxide; In tetrahydrofuran; pyridine; dichloromethane; acetone; acetonitrile;

upstream raw materials:

5-Benzyloxy-3-(4-hydroxymethylphenoxy)-4-methoxybenzylalkohol

triphenylphosphine

5-Benzyloxy-3-(4-brommethylphenoxy)-4-methoxybenzylbromid

4-methoxycarbonylphenyl bromide

Downstream raw materials:

3-Benzyloxy-5-<(3-benzyloxyphenyl)ethenyl>-1-<4-<2-(3-benzyloxyphenyl)ethenyl>phenoxy>-2-methoxybenzol

perrottetin G

Perrottetin G triacetat