1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid

Base Information

Chemical Name:1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid
CAS No.:862574-89-8
Molecular Formula:C11H10O4
Molecular Weight:206.198
Hs Code.:2932999099
European Community (EC) Number:807-215-6
DSSTox Substance ID:DTXSID90559254
Wikidata:Q82441914
Mol file:862574-89-8.mol

Synonyms:862574-89-8;1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid;1-(1,3-BENZODIOXOL-5-YL)CYCLOPROPANECARBOXYLIC ACID;1-Benzo[1,3]dioxol-5-yl-cyclopropanecarboxylic acid;MFCD09907922;1-(1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid;1-(2H-1,3-BENZODIOXOL-5-YL)CYCLOPROPANE-1-CARBOXYLIC ACID;1-(benzo[d)[1,3]dioxol-6-yl)cyclopropanecarboxylic acid;1-(BENZO[D][1,3]DIOXOL-6-YL)CYCLOPROPANECARBOXYLIC ACID;SCHEMBL699497;1-(1,3-Benzodioxol-5-yl)cyclopropane-carboxylic acid;DTXSID90559254;NZZVDTIYQUASAT-UHFFFAOYSA-N;AKOS009265992;AB54698;SY104767;CS-0088378;EN300-399079;A915001;A1-00530;1-(1,3-Benzodioxol-5-yl)cyclopropane-carboxylic acid;1-benzo[1,3]-dioxol-5-yl-cyclopropanecarboxylic acid;1-Benzo[1,3]dioxo1-5-yl-cyclopropanecarboxylic Acid;1-(1,3-dioxaindan-5-yl)cyclopropane-1-carboxylic acid;Z361883704;1-(1,3-BENZODIOXOL-5-YL)CYCLOPROPANECARBOXYLICACID;1-(benzo[d][1,3]dioxol-5-yl)-cyclopropanecarboxylic acid;1-BENZOL[1,3]DIOXOL-5-YL-CYCLOPROPANECARBOXYLIC ACID

Suppliers and Price of 1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylicacid 95+%
1g
$ 464.00

Crysdot
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylicacid 95+%
250mg
$ 252.00

Chemenu
1-(1,3-Benzodioxol-5-yl)cyclopropane-carboxylicacid 95%
1g
$ 825.00

Biosynth Carbosynth
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid
50 mg
$ 93.00

Biosynth Carbosynth
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid
25 mg
$ 53.00

Biosynth Carbosynth
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid
250 mg
$ 325.00

Biosynth Carbosynth
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid
500 mg
$ 565.00

American Custom Chemicals Corporation
1-BENZO[1,3]DIOXOL-5-YL-CYCLOPROPANECARBOXYLIC ACID 95.00%
5MG
$ 504.52

Alichem
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylicacid
250mg
$ 191.76

Alichem
1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylicacid
1g
$ 890.82

Total 13 raw suppliers

Chemical Property of 1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid

Chemical Property:

PSA：55.76000
LogP:1.53150
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:206.05790880
Heavy Atom Count:15
Complexity:284

Purity/Quality:

99%, ^*data from raw suppliers

1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1(C2=CC3=C(C=C2)OCO3)C(=O)O
Uses Used as a reagent in the preparation of N-pyridinyl carboxamide derivatives as modulators of ATP-binding cassette transporters.

Technology Process of 1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid

There total 9 articles about 1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1-(1-(benzo[d][1,3]dioxol-5-yl)cyclopropyl)ethanone

: 862574-89-8
1-(2H-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid

Guidance literature:: With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide; In tetrachloromethane; dichloromethane; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1021/acs.joc.8b00297

Reference yield: 80.1%

: 107-04-0
1-Bromo-2-chloroethane

: 4421-09-4
piperonylonitrile

: 862574-89-8
1-(2H-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid

Guidance literature:: 1-Bromo-2-chloroethane; piperonylonitrile; With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In water; at 70 - 130 ℃; for 112h;

With hydrogenchloride; In water; pH=< 1;

Reference yield: 80.0%

: 107-04-0
1-Bromo-2-chloroethane

: 4439-02-5
3,4-methylenedioxyphenylacetonitrile

: 862574-89-8
1-(2H-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid

Guidance literature:: 1-Bromo-2-chloroethane; 3,4-methylenedioxyphenylacetonitrile; With sodium hydroxide; water; N-benzyl-N,N,N-triethylammonium chloride; at 70 - 130 ℃; for 72h;

With hydrogenchloride; In water;