(S)-(-)-1-Amino-1-phenylpropaneHCl

Base Information

• Chemical Name: (S)-(-)-1-Amino-1-phenylpropaneHCl
• CAS No.: 19146-52-2
• Molecular Formula: C9H14ClN
• Molecular Weight: 171.67
• Hs Code.: 2921499090
• Mol file: 19146-52-2.mol

Synonyms:(1S)-1-Phenylpropan-1-amine hydrochloride;(S)-alpha-Ethylbenzenemethanamine hydrochloride;

Chemical Property of (S)-(-)-1-Amino-1-phenylpropaneHCl

Chemical Property:

• PSA: 26.02000
• LogP: 3.59870
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-(-)-1-Amino-1-phenylpropaneHCl

There total 20 articles about (S)-(-)-1-Amino-1-phenylpropaneHCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(RS)-2-methyl-N-((S)-1-phenylpropyl)propane-2-sulfinamide (196929-97-2) → (1S)-1-phenylpropan-1-amine hydrochloride (19146-52-2)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃;

DOI:10.1021/jo0609834

Reference yield: 88.0%

diethylzinc (557-20-0) + benzaldehyde (100-52-7) → (1S)-1-phenylpropan-1-amine hydrochloride (19146-52-2)

Guidance literature:

diethylzinc; benzaldehyde; With chiral Cu(BozPHOS)2OTf; diphenylphosphinamide; In toluene; at 25 ℃; for 24h;

With hydrogenchloride; In toluene; for 8h;

DOI:10.1021/jo0516483

Reference yield: 88.0%

(S)-N-(1-phenylpropyl)-P,P-diphenylphosphinamide (106651-15-4) → (1S)-1-phenylpropan-1-amine hydrochloride (19146-52-2)

Guidance literature:

With hydrogenchloride; In methanol; water; at 20 ℃; for 16.5h;

DOI:10.15227/orgsyn.083.0005

upstream raw materials:

ethyl bromide

benzhydrylidene-benzyl-amine

(R_S)-2-methyl-N-((S)-1-phenylpropyl)propane-2-sulfinamide

ethylmagnesium bromide

Downstream raw materials:

(R_S)-2-methyl-N-((S)-1-phenylpropyl)propane-2-sulfinamide