Ethyl 2-ethoxymethylene-4,4-difluoro-3-oxobutyrate

Base Information

Chemical Name:Ethyl 2-ethoxymethylene-4,4-difluoro-3-oxobutyrate
CAS No.:176969-33-8
Molecular Formula:C9H12F2O4
Molecular Weight:222.19
Hs Code.:2918990090
European Community (EC) Number:619-794-0
Mol file:176969-33-8.mol

Synonyms:Ethyl 2-(ethoxymethylene)-4,4-difluoro-3-oxobutanoate;SCHEMBL19246;C9H12F2O4;Butanoic acid, 2-(ethoxymethylene)-4,4-difluoro-3-oxo-, ethyl ester;SB85780;Ethyl 2-Ethoxymethylenedifluoroacetoacetate;Ethyl 2-ethoxymethylene-4,4-difluoro-3-oxobutyrate;ethyl 2-ethoxymethylene-4,4-difluoro-3-oxo-butyrate;ethyl alpha-ethoxymethylene-4,4-difluoro-3-oxobutyrate

Suppliers and Price of Ethyl 2-ethoxymethylene-4,4-difluoro-3-oxobutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Ethyl 2-(ethoxymethylene)-4,4-difluoro-3-oxobutyrate 97%
5 g
$ 395.00

SynQuest Laboratories
Ethyl 2-(ethoxymethylene)-4,4-difluoro-3-oxobutyrate 97%
1 g
$ 125.00

Crysdot
Ethyl2-(ethoxymethylene)-4,4-difluoro-3-oxobutanoate 95+%
5g
$ 520.00

Chemenu
Ethyl2-(ethoxymethylene)-4,4-difluoro-3-oxobutanoate 95%
5g
$ 473.00

American Custom Chemicals Corporation
ETHYL-2-(ETHOXYMETHYLENE)-4,4-DIFLUORO-3-OXOBUTANOATE 95.00%
5MG
$ 496.50

Total 35 raw suppliers

Chemical Property of Ethyl 2-ethoxymethylene-4,4-difluoro-3-oxobutyrate

Chemical Property:

Vapor Pressure:0.0242mmHg at 25°C
Boiling Point:248℃
Flash Point:101℃
PSA：52.60000
Density:1.177
LogP:1.30410
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:222.07036518
Heavy Atom Count:15
Complexity:261

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 2-(ethoxymethylene)-4,4-difluoro-3-oxobutyrate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC=C(C(=O)C(F)F)C(=O)OCC

Technology Process of Ethyl 2-ethoxymethylene-4,4-difluoro-3-oxobutyrate

There total 6 articles about Ethyl 2-ethoxymethylene-4,4-difluoro-3-oxobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 352-24-9
ethyl 4,4-difluoro-3-oxobutyrate

: 122-51-0
orthoformic acid triethyl ester

: 176969-33-8
(E/Z)-ethyl 2-(ethoxymethylene)-4,4-difluoro-3-oxobutanoate

Guidance literature:: With acetic anhydride; for 5h; Reflux;

Reference yield: 97.9%

: 1001-26-9
ethyl 3-ethoxyacrylate

: 2925-22-6
2,2-difluoroacetyl fluoride

: 176969-33-8
(E/Z)-ethyl 2-(ethoxymethylene)-4,4-difluoro-3-oxobutanoate

Guidance literature:: With trihexyl(tetradecyl) phosphonium hydroxide; In toluene; at -10 - 10 ℃; for 2h; Reagent/catalyst; Temperature; Solvent; Concentration;