2-Oxopyridine

Base Information

• Chemical Name: 2-Oxopyridine
• CAS No.: 1199357-22-6
• Molecular Formula: C₅H₅NO
• Molecular Weight: 95.1008
• Mol file: 1199357-22-6.mol

Synonyms:

Chemical Property of 2-Oxopyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Oxopyridine

There total 119 articles about 2-Oxopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

2-acetoxypyridine (3847-19-6) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 2-Pyridone (142-08-5,1199357-22-6) + 1-methyl-2-pyridone (694-85-9,859803-97-7) + N-acetyl-N-methylaniline (579-10-2) + 4'-dimethylaminoacetophenone (2124-31-4)

Guidance literature:

at 255 ℃; Further byproducts given;

Reference yield: 33.0%

2-acetoxypyridine (3847-19-6) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 2-Pyridone (142-08-5,1199357-22-6) + 1-methyl-2-pyridone (694-85-9,859803-97-7) + [1,2']bipyridinyl-2-one (3480-65-7) + N-acetyl-N-methylaniline (579-10-2) + 4,4'-methylene-bis(N,N-dimethylaniline) (101-61-1) + 4'-dimethylaminoacetophenone (2124-31-4)

Guidance literature:

at 255 ℃; Product distribution; other N,N-dialkylanilines;

Reference yield: 31.0%

pyridine N-oxide (694-59-7) → pyridine (110-86-1) + 2-Pyridone (142-08-5,1199357-22-6) + pyridine-2-acetonitrile (2739-97-1) + [2,2]bipyridinyl (366-18-7) + pyrrole (109-97-7,30604-81-0)

Guidance literature:

at 750 - 850 ℃; under 0.001 - 0.01 Torr; Product distribution; Mechanism;

upstream raw materials:

pyridine N-oxide

acetic anhydride

6-Hydroxypicolinic acid

6-hydroxy-3-pyridinecarboxylic acid

Downstream raw materials:

(pyridin-2-yloxy)acetic acid ethyl ester

(2-oxo-2H-pyridin-1-yl)-acetic acid ethyl ester

1-(2-diethylamino-ethyl)-1H-pyridin-2-one

2-(2'-diethylamino-ethanoxy)pyridine

Refernces

• 1、 Suggs, J.William,Pearson. "Limits on the transition state geometry for metal insertion into a carbon-hydrogen bond". . p. 3853 - 3856. Retrieved 1980.
• 2、 Stoyanov,Stoyanova,Antonov,Karagiannidis,Akrivos. "Thione-Disulfide Interchange of some Heterocyclic Tautomeric Thiones and their Symmetrical Bisulfides". . p. 495 - 504. Retrieved 1996.
• 3、 Kaneko, Chikara,Naito, Toshihiko,Saito, Akemi. "THREE-STEP SYNTHESIS OF 4-(2'-HYDROXYETHYL)AZETIDIN-2-ONE AND ITS SUBSTITUTED DERIVATIVES FROM 4-ACETOXY-2-PYRIDONES". . p. 1591 - 1594. Retrieved 1984.
• 4、 Peck, Douglas G.,Mehta, Anil J.,Johnston, Keith P.. "Pressure Tuning of Chemical Reaction Equilibria in Supercritical Fluids". . p. 4297 - 4304. Retrieved 1989.
• 5、 Gillard, R. D.,Hall, D. P. J.. "Simple Oxidations of Pyridines: Zinc Sulphates or Natural Sand as Remarkably Specific Catalysts". . p. 1163 - 1164. Retrieved 1988.
• 6、 Wahren. "-". . p. 441. Retrieved 1968.
• 7、 Markgraf et al.. "-". . p. 958. Retrieved 1963.
• 8、 Kibet, Joshua K.,Khachatryan, Lavrent,Dellinger, Barry. "Molecular products from the thermal degradation of glutamic acid". . p. 7696 - 7704. Retrieved 2013/09/02.