6-Chloro-5-(trifluoromethyl)pyridin-3-amine

Base Information

Chemical Name:6-Chloro-5-(trifluoromethyl)pyridin-3-amine
CAS No.:99368-68-0
Molecular Formula:C6H4ClF3N2
Molecular Weight:196.56
Hs Code.:2933399090
European Community (EC) Number:875-530-6
DSSTox Substance ID:DTXSID30543137
Wikidata:Q72460373
Mol file:99368-68-0.mol

Synonyms:6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE;99368-68-0;MFCD11101042;5-Amino-2-chloro-3-trifluoromethylpyridine;SCHEMBL909629;DTXSID30543137;AMY26333;AKOS006308154;AB63177;CS-W022488;AC-29078;DS-16971;SY107757;3-Amino-6-chloro-5-(trifluoromethyl)pyridine;6-chloro-5-(trifluoromethyl)pyridine-3-amine;EN300-252484;6-Chloro-5-(trifluoromethyl)pyridin-3-amine, 98%;J-518580;6-CHLORO-5-TRIFLUOROMETHYL-PYRIDIN-3-YLAMINE

Suppliers and Price of 6-Chloro-5-(trifluoromethyl)pyridin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-5-(trifluoromethyl)pyridin-3-amine
100mg
$ 65.00

TRC
6-Chloro-5-(trifluoromethyl)pyridin-3-amine
50mg
$ 55.00

SynQuest Laboratories
6-Chloro-5-(trifluoromethyl)pyridin-3-amine 95.0%
100 mg
$ 109.00

Matrix Scientific
6-Chloro-5-(trifluoromethyl)pyridin-3-amine 95+%
5g
$ 1674.00

Matrix Scientific
6-Chloro-5-(trifluoromethyl)pyridin-3-amine 95+%
1g
$ 558.00

Matrix Scientific
6-Chloro-5-(trifluoromethyl)pyridin-3-amine 95+%
250mg
$ 224.00

Labseeker
6-chloro-5-(trifluoromethyl)pyridin-3-amine 98
1g
$ 300.00

Crysdot
6-Chloro-5-(trifluoromethyl)pyridin-3-amine 95+%
5g
$ 866.00

Crysdot
6-Chloro-5-(trifluoromethyl)pyridin-3-amine 95+%
1g
$ 285.00

Chemcia Scientific
6-Chloro-5-trifluoromethyl-pyridin-3-ylamine 95%
1 g
$ 260.00

Total 40 raw suppliers

Chemical Property of 6-Chloro-5-(trifluoromethyl)pyridin-3-amine

Chemical Property:

Boiling Point:292.083 °C at 760 mmHg
Flash Point:130.448 °C
PSA：38.91000
Density:1.507 g/cm³
LogP:2.91720
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:196.0015103
Heavy Atom Count:12
Complexity:161

Purity/Quality:

97% ^*data from raw suppliers

6-Chloro-5-(trifluoromethyl)pyridin-3-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC(=C1C(F)(F)F)Cl)N

Technology Process of 6-Chloro-5-(trifluoromethyl)pyridin-3-amine

There total 10 articles about 6-Chloro-5-(trifluoromethyl)pyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 99368-67-9
2-chloro-5-nitro-3-(trifluoromethyl)pyridine

: 99368-68-0
6-chloro-5-(trifluoromethyl)pyridin-3-amine

Guidance literature:: With iron; ammonium chloride; In ethanol; water; at 80 ℃; for 4h;

Reference yield:

: 99368-66-8
2-hydroxyl-5-nitro-3-(trifluoromethyl)pyridine

: 99368-68-0
6-chloro-5-(trifluoromethyl)pyridin-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / N,N-dimethyl-formamide / 10 h / 100 °C

2: iron; acetic acid / 0.25 h / 80 °C

With thionyl chloride; iron; acetic acid; In N,N-dimethyl-formamide;

Reference yield:

: 25391-58-6
2-hydroxy-3-iodo-5-nitropyridine

: 99368-68-0
6-chloro-5-(trifluoromethyl)pyridin-3-amine

Guidance literature:: Multi-step reaction with 3 steps

1: phosphorus pentachloride; trichlorophosphate / 0.75 h / 140 °C

2: copper(l) iodide / N,N-dimethyl-formamide / 19 h / 70 °C

3: hydrogen / 5 % platinum on carbon; zinc dibromide / ethyl acetate / 20 h

With copper(l) iodide; phosphorus pentachloride; hydrogen; trichlorophosphate; 5 % platinum on carbon; zinc dibromide; In ethyl acetate; N,N-dimethyl-formamide;