3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile

Base Information

Chemical Name:3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile
CAS No.:1149380-46-0
Molecular Formula:C13H8N4
Molecular Weight:220.233
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50701939
Wikidata:Q82633717
Mol file:1149380-46-0.mol

Synonyms:3-(imidazo[1,2-b]pyridazin-2-yl)benzonitrile;1149380-46-0;3-imidazo[1,2-b]pyridazin-2-ylBenzonitrile;SCHEMBL44375;DTXSID50701939;LIZGECYXCHZNJQ-UHFFFAOYSA-N;FT-0703479

Suppliers and Price of 3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile 95+%
1g
$ 772.00

American Custom Chemicals Corporation
3-(IMIDAZO[1,2-B]PYRIDAZIN-2-YL)BENZONITRILE 95.00%
5MG
$ 502.49

Alichem
3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile
1g
$ 615.44

Total 7 raw suppliers

Chemical Property of 3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile

Chemical Property:

PSA：53.98000
LogP:2.26798
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:220.074896272
Heavy Atom Count:17
Complexity:321

Purity/Quality:

99% ^*data from raw suppliers

3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C2=CN3C(=N2)C=CC=N3)C#N

Technology Process of 3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile

There total 3 articles about 3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.5%

: 1125406-99-6
3-(6-chloro-imidazo[1,2-b]pyridazin-2-yl)-benzonitrile

: 1149380-46-0
3-(imidazo[1,2-b]pyridazin-2-yl)benzonitrile

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; methanol; at 20 ℃; for 4 - 6h; Product distribution / selectivity;

Reference yield:

: 50916-55-7
3-(2-bromoacetyl)benzonitrile

: 1149380-46-0
3-(imidazo[1,2-b]pyridazin-2-yl)benzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 10 h / Reflux

2: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol / 5 h / 20 °C

With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; methanol; ethanol;

Reference yield:

: 6136-68-1
3-acethylbenzonitrile

: 1149380-46-0
3-(imidazo[1,2-b]pyridazin-2-yl)benzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: bromine / diethyl ether / 4 h / 0 - 20 °C

2: ethanol / 10 h / Reflux

3: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol / 5 h / 20 °C

With hydrogen; bromine; palladium 10% on activated carbon; In tetrahydrofuran; methanol; diethyl ether; ethanol;