4-Bromo-3-methylthiophenecarboxylic acid

Base Information

Chemical Name:4-Bromo-3-methylthiophenecarboxylic acid
CAS No.:265652-39-9
Molecular Formula:C6H5BrO2S
Molecular Weight:221.07
Hs Code.:
European Community (EC) Number:673-633-9
DSSTox Substance ID:DTXSID20373723
Wikidata:Q82162035
Mol file:265652-39-9.mol

Synonyms:265652-39-9;4-Bromo-3-methylthiophenecarboxylic acid;4-bromo-3-methylthiophene-2-carboxylic acid;2-Thiophenecarboxylic acid, 4-bromo-3-methyl-;4-bromo-3-methyl-thiophene-2-carboxylic Acid;MFCD03789231;4-Bromo-3-methylthiophenecarboxylicacid;4-bromo-3-methyl-2-thiophenecarboxylic acid;SCHEMBL321098;AMY7345;DTXSID20373723;TUVDPNVBUMLEHW-UHFFFAOYSA-N;AKOS015898832;FS-1605;SB66904;SY063565;4-bromo-3-mehylthiophene-2-carboxylic acid;CS-0068006;FT-0746545;EN300-320973;H10542;A818512;J-016477;4-bromo-3-methylthiophenecarboxylic acid, AldrichCPR

Suppliers and Price of 4-Bromo-3-methylthiophenecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Oakwood
4-Bromo-3-methylthiophenecarboxylic acid
25g
$ 820.00

Oakwood
4-Bromo-3-methylthiophenecarboxylic acid
5g
$ 205.00

Oakwood
4-Bromo-3-methylthiophenecarboxylic acid
1g
$ 95.00

Oakwood
4-Bromo-3-methylthiophenecarboxylic acid
250mg
$ 48.00

Crysdot
4-Bromo-3-methylthiophene-2-carboxylicacid 95+%
10g
$ 351.00

American Custom Chemicals Corporation
4-BROMO-3-METHYLTHIOPHENECARBOXYLIC ACID 98.00%
25G
$ 1715.18

AK Scientific
4-Bromo-3-methylthiophenecarboxylicacid
2.5g
$ 368.00

AHH
4-Bromo-3-methylthiophenecarboxylicacid 98%
25g
$ 320.00

Total 23 raw suppliers

Chemical Property of 4-Bromo-3-methylthiophenecarboxylic acid

Chemical Property:

Vapor Pressure:0.000106mmHg at 25°C
Refractive Index:1.629
Boiling Point:323.674 °C at 760 mmHg
Flash Point:149.553 °C
PSA：65.54000
Density:1.784 g/cm³
LogP:2.51720
Storage Temp.:2-8°C(protect from light)
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:219.91936
Heavy Atom Count:10
Complexity:151

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-3-methylthiophenecarboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(SC=C1Br)C(=O)O

Technology Process of 4-Bromo-3-methylthiophenecarboxylic acid

There total 5 articles about 4-Bromo-3-methylthiophenecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 265652-38-8
methyl 4-bromo-3-methylthiophene-2-carboxylate

: 265652-39-9
3-methyl-4-bromo-2-thiophenecarboxylic acid

Guidance literature:: With methanol; lithium hydroxide; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

: 265652-37-7
ethyl 4-bromo-3-methyl-2-thiophenecarboxylate

: 265652-39-9
3-methyl-4-bromo-2-thiophenecarboxylic acid

Guidance literature:: With hydrogenchloride; sodium hydroxide; In tetrahydrofuran; methanol; water;

Reference yield:

: 81452-54-2
methyl 3-methylthiophene-2-carboxylate

: 265652-39-9
3-methyl-4-bromo-2-thiophenecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid; sodium hydroxide; bromine / 6 h / 60 - 85 °C

1.2: 1 h / 50 - 85 °C

2.1: lithium hydroxide; water / tetrahydrofuran / 2 h / 20 °C

With water; bromine; acetic acid; sodium hydroxide; lithium hydroxide; In tetrahydrofuran;