5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid

Base Information

Chemical Name:5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid
CAS No.:244638-94-6
Molecular Formula:C₇H₆INO₃
Molecular Weight:279.034
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50592864
Wikidata:Q72483993
Mol file:244638-94-6.mol

Synonyms:244638-94-6;5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid;5-iodo-6-methyl-4-oxo-1H-pyridine-3-carboxylic acid;SCHEMBL1146532;SCHEMBL10200721;DTXSID50592864;KNUZTACRVSYPNI-UHFFFAOYSA-N;5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylicacid;AKOS016012531;DA-07748;1,4-dihydro-3-iodo-2-methyl-4-oxo-5-pyridinecarboxylic acid

Suppliers and Price of 5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylicacid 95+%
1g
$ 772.00

Chemenu
5-iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylicacid 95%
1g
$ 729.00

American Custom Chemicals Corporation
5-IODO-6-METHYL-4-OXO-1,4-DIHYDROPYRIDINE-3-CARBOXYLIC ACID 95.00%
5MG
$ 495.04

Alichem
5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylicacid
1g
$ 640.56

Total 5 raw suppliers

Chemical Property of 5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid

Chemical Property:

PSA：70.16000
LogP:0.98610
Storage Temp.:2-8°C
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:278.93924
Heavy Atom Count:12
Complexity:317

Purity/Quality:

99% ^*data from raw suppliers

5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)C(=CN1)C(=O)O)I

Technology Process of 5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid

There total 4 articles about 5-Iodo-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 33821-58-8
6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid

: 244638-94-6,868363-06-8
1,4-Dihydro-3-iodo-2-methyl-4-oxo-5-pyridinecarboxylic acid

Guidance literature:: With Iodine monochloride; sodium hydrogensulfite; calcium carbonate; In N,N-dimethyl-formamide;

Reference yield:

: 67367-33-3
4-hydroxy-6-methylnicotinic acid

: 868363-06-8,244638-94-6
4-hydroxy-5-iodo-6-methyl-nicotinic acid

Guidance literature:: With Iodine monochloride; calcium carbonate; In N,N-dimethyl-formamide; at 50 ℃;
DOI:10.1016/j.bmcl.2005.08.006

Reference yield:

: 675-10-5
4-hydroxy-6-methyl-2-pyron

: 868363-06-8,244638-94-6
4-hydroxy-5-iodo-6-methyl-nicotinic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: DMA / dioxane

2.1: aq. NH₃

2.2: NHMe₂ / 50 °C

2.3: H₂SO₄

3.1: iodine monochloride; CaCO₃ / dimethylformamide / 50 °C

With ammonium hydroxide; Iodine monochloride; 2,4-dichlorophenoxyacetic acid dimethylamine; calcium carbonate; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2005.08.006