3-Hydroxypyridine-2,6-dicarboxylic acid

Base Information

• Chemical Name: 3-Hydroxypyridine-2,6-dicarboxylic acid
• CAS No.: 71502-30-2
• Molecular Formula: C₇H₅NO₅
• Molecular Weight: 183.12
• DSSTox Substance ID: DTXSID50601708
• Wikidata: Q72481592
• Mol file: 71502-30-2.mol

Synonyms:71502-30-2;3-Hydroxypyridine-2,6-dicarboxylic acid;SCHEMBL8834235;DTXSID50601708;3-Hydroxy-2,6-pyridinedicarboxylic acid;DA-18838

Chemical Property of 3-Hydroxypyridine-2,6-dicarboxylic acid

Chemical Property:

• Melting Point: 250 oC (approx)
• Density: 1.725±0.06 g/cm3 (20 oC 760 Torr)
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 183.01677226
• Heavy Atom Count: 13
• Complexity: 229

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=NC(=C1O)C(=O)O)C(=O)O

Technology Process of 3-Hydroxypyridine-2,6-dicarboxylic acid

There total 2 articles about 3-Hydroxypyridine-2,6-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-bis-(hydroxymethyl)-3-hydroxypyridine (38029-16-2) → 3-hydroxy-pyridine-2,6-dicarboxylic acid (71502-30-2)

Guidance literature:

With potassium permanganate;

Reference yield:

2,6-diiodo-3-hydroxypyridine (14764-90-0) → 3-hydroxy-pyridine-2,6-dicarboxylic acid (71502-30-2)

Guidance literature:

With pyridine; Erhitzen des Reaktionsprodukts mit wss. KOH;

Reference yield:

3-hydroxy-pyridine-2,6-dicarboxylic acid (71502-30-2) → 3-HYDROXYPYRIDINE (109-00-2)

Guidance literature:

at 230 ℃;

upstream raw materials:

2,6-bis-(hydroxymethyl)-3-hydroxypyridine

2,6-diiodo-3-hydroxypyridine

Downstream raw materials:

3-HYDROXYPYRIDINE