4-[2-Methoxycarbonyl-2-(BOC-amino)ethyl]phenylboronic acid pinacol ester

Base Information

Chemical Name:4-[2-Methoxycarbonyl-2-(BOC-amino)ethyl]phenylboronic acid pinacol ester
CAS No.:220587-29-1
Molecular Formula:C21H32BNO6
Molecular Weight:405.299
Hs Code.:
European Community (EC) Number:889-129-9
Mol file:220587-29-1.mol

Synonyms:335030-22-3;4-[2-Methoxycarbonyl-2-(BOC-amino)ethyl]phenylboronic acid pinacol ester;220587-29-1;methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoate;SCHEMBL539840;(s)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate;BCP19729;AB88468;AB89340;AT29520;SB17957;BS-28491;CS-0174677;4-[2-Methoxycarbonyl-2-(BOC-amino)ethyl]phenylboronicacidpinacolester;Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate

Suppliers and Price of 4-[2-Methoxycarbonyl-2-(BOC-amino)ethyl]phenylboronic acid pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Methyl2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate 95+%
1g
$ 743.00

ChemScene
L-Phenylalanine,N-[(1,1-dimethylethoxy)carbonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-,methylester
250mg
$ 685.00

ChemScene
L-Phenylalanine,N-[(1,1-dimethylethoxy)carbonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-,methylester
100mg
$ 411.00

ChemScene
L-Phenylalanine,N-[(1,1-dimethylethoxy)carbonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-,methylester
50mg
$ 248.00

ChemScene
L-Phenylalanine,N-[(1,1-dimethylethoxy)carbonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-,methylester
1g
$ 1370.00

Alichem
(S)-Methyl2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate
1g
$ 802.50

Total 21 raw suppliers

Chemical Property of 4-[2-Methoxycarbonyl-2-(BOC-amino)ethyl]phenylboronic acid pinacol ester

Chemical Property:

Boiling Point:521.897 °C at 760 mmHg
PKA:10.96±0.46(Predicted)
Flash Point:269.434 °C
PSA：86.58000
Density:1.109 g/cm³
LogP:2.79900
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:405.2322679
Heavy Atom Count:29
Complexity:577

Purity/Quality:

97% ^*data from raw suppliers

(S)-Methyl2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)CC(C(=O)OC)NC(=O)OC(C)(C)C

Technology Process of 4-[2-Methoxycarbonyl-2-(BOC-amino)ethyl]phenylboronic acid pinacol ester

There total 20 articles about 4-[2-Methoxycarbonyl-2-(BOC-amino)ethyl]phenylboronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 112766-18-4
methyl N-(tert-butoxycarbonyl)-O-[(trifluoromethyl)sulfonyl]-L-tyrosinate

: 73183-34-3
bis(pinacol)diborane

: 220587-29-1,335030-24-5
methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate

Guidance literature:: With potassium acetate; palladium diacetate; tricyclohexylphosphine; In acetonitrile; for 5h; Reflux; Large scale;
DOI:10.1021/acs.oprd.9b00520

Reference yield: 100.0%

: 73183-34-3
bis(pinacol)diborane

: 266306-18-7
(S)-3-(4-Bromo-phenyl)-2-tert-butoxycarbonylamino-propionic acid methyl ester

: 220587-29-1,335030-24-5
methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 90 ℃; Inert atmosphere; Sealed tube;

Reference yield: 94.0%

: 112766-18-4
methyl N-(tert-butoxycarbonyl)-O-[(trifluoromethyl)sulfonyl]-L-tyrosinate

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 220587-29-1,335030-24-5
methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate

Guidance literature:: With 4-methyl-morpholine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; dichloromethane; at 80 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.tetlet.2010.01.006