2-[(tert-Butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

Base Information

Chemical Name:2-[(tert-Butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate
CAS No.:134807-64-0
Molecular Formula:C₁₅H₂₃NO₅S
Molecular Weight:329.417
Hs Code.:
DSSTox Substance ID:DTXSID70551296
Mol file:134807-64-0.mol

Synonyms:SCHEMBL272612;DTXSID70551296;2-[(tert-Butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate;AKOS005146039;SB49715;134807-64-0

Suppliers and Price of 2-[(tert-Butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-[(tert-Butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

Chemical Property:

Vapor Pressure:1.37E-10mmHg at 25°C
Refractive Index:1.519
Boiling Point:511.8°C at 760 mmHg
Flash Point:263.4°C
Density:1.185g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:329.12969401
Heavy Atom Count:22
Complexity:444

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=CC=C1)COS(=O)(=O)C

Technology Process of 2-[(tert-Butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

There total 15 articles about 2-[(tert-Butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 66605-57-0
(S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol

: 124-63-0
methanesulfonyl chloride

: 126301-19-7,134807-64-0,109687-66-3
(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 0.33h;
DOI:10.1021/jo00226a007

Reference yield: 70.0%

: 66605-57-0
(S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol

: 7143-01-3
Methanesulfonic anhydride

: 126301-19-7,134807-64-0,109687-66-3
(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 3h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 126301-19-7,134807-64-0,109687-66-3
(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / Ambient temperature

2: TEA / CH₂Cl₂ / Ambient temperature

With TEA; In tetrahydrofuran; dichloromethane;