4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine

Base Information

Chemical Name:4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine
CAS No.:853784-23-3
Molecular Formula:C₇H₇F₃N₂O
Molecular Weight:192.141
Hs Code.:
Mol file:853784-23-3.mol

Synonyms:3-Trifluoromethyl-4,5,6,7-tetrahydroisoxazol[3,4-c]pyridine;4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine

Suppliers and Price of 4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine

Chemical Property:

Boiling Point:227℃
Flash Point:91℃
PSA：38.06000
Density:1.354
LogP:1.66790

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine

There total 1 articles about 4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 647863-25-0
tert-butyl 3-oxo-4-(2,2,2-trifluoroacetyl)piperidine-1-carboxylate

: 853784-23-3
3-trifluoromethyl-4,5,6,7-tetrahydro-isoxazolo[3,4-c]pyridine

Guidance literature:: With hydroxylamine; acetic acid; for 6h; Heating / reflux;

Reference yield:

: 853784-23-3
3-trifluoromethyl-4,5,6,7-tetrahydro-isoxazolo[3,4-c]pyridine

: 3-amino-4-(2,5-difluoro-phenyl)-1-(3-trifluoromethyl-4,5-dihydro-7H-isoxazolo[3,4-c]pyridin-6-yl)-butan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: iPr₂NEt / CH₂Cl₂

2: HCl / dioxane

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane;
DOI:10.1016/j.bmcl.2005.03.012