butyl 2-aminopropanoate

Base Information

• Chemical Name: butyl 2-aminopropanoate
• CAS No.: 174468-17-8
• Molecular Formula: C7H15NO2
• Molecular Weight: 145.1995
• Mol file: 174468-17-8.mol

Synonyms:butyl 2-aminopropanoate

Chemical Property of butyl 2-aminopropanoate

Chemical Property:

• PSA: 52.32000
• LogP: 1.37720

Purity/Quality:

99%min ^*data from raw suppliers

BUTYL-2-AMINOPROPANOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of butyl 2-aminopropanoate

There total 1 articles about butyl 2-aminopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rac-Ala-OH (302-72-7,25191-17-7,18875-37-1) + butan-1-ol (71-36-3) → 2-aminopropionic acid butyl ester hydrochloride (81305-85-3,174468-17-8)

Guidance literature:

With hydrogenchloride;

Reference yield: 78.6%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + (S)-butyl 2-aminopropanoate hydrochloride (174468-17-8) + O-phenyl phosphorodichloridate (770-12-7) → (2S)-butyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate (1439900-37-4)

Guidance literature:

(S)-butyl 2-aminopropanoate hydrochloride; O-phenyl phosphorodichloridate; In dichloromethane; at -30 ℃; for 0.166667h; Inert atmosphere;

With triethylamine; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere;

4-nitro-phenol; With triethylamine; In dichloromethane; at 20 ℃; for 72h; Inert atmosphere;

Reference yield: 56.0%

1-octanoylindoline-2,3-dione (23806-38-4) + (S)-alanine n-butyl ester hydrochloride (174468-17-8) → butyl 2-(2-(2-octanamidophenyl)-2-oxoacetamido)propanoate

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; water; at 5 - 20 ℃;

DOI:10.1016/j.tet.2013.07.052

upstream raw materials:

rac-Ala-OH

butan-1-ol

Downstream raw materials:

(2S)-butyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate

(2S)-2-(((perfluorophenoxy)(phenoxy)phosphoryl)amino)propionic acid butyl ester

Refernces