1-Isobutyl-1H-imidazo[4,5-c]quinoline

Base Information

Chemical Name:1-Isobutyl-1H-imidazo[4,5-c]quinoline
CAS No.:99010-24-9
Molecular Formula:C14H15N3
Molecular Weight:225.293
Hs Code.:2933990090
UNII:GLE3AF1XOT
ChEMBL ID:CHEMBL191609
DSSTox Substance ID:DTXSID20465455
Wikidata:Q82291409
Mol file:99010-24-9.mol

Synonyms:1-Isobutyl-1H-imidazo[4,5-c]quinoline;99010-24-9;Desamino Imiquimod;1-(2-methylpropyl)imidazo[4,5-c]quinoline;Deaminoimiquimod;GLE3AF1XOT;1H-Imidazo[4,5-c]quinoline, 1-(2-methylpropyl)-;1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE;MFCD08460216;1-Isobutyl-1H-imidazo(4,5-C)quinoline;1-(2-Methylpropyl)imidazo(4,5-C)quinoline;1-(2-Methylpropyl)-1H-imidazo(4,5-C)quinoline;1H-Imidazo(4,5-C)quinoline, 1-(2-methylpropyl)-;1-Isobutyl-1H-imidazo[4,5-c]quinoline (Desaminoimiquimod);1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinoline;1-Isobutyl-1H-imidazo-[4,5-c]-quinoline;Imiquimod Related Compound A (USP);Imiquimod Related Compound A;Deaminoimiquimod [USP];UNII-GLE3AF1XOT;SCHEMBL564029;CHEMBL191609;DTXSID20465455;CXYOCSTZCULCAE-UHFFFAOYSA-N;BCP17368;AKOS015963993;AB91862;CS-W003531;DEAMINOIMIQUIMOD [USP IMPURITY];AC-28200;DS-18403;SY028932;FT-0741201;1-Isobutyl-1H-imidazo[4 pound not5-c]quinoline;1-(2-Methylpropyl)-1H -imidazo[4,5-c]quinoline;A858503

Suppliers and Price of 1-Isobutyl-1H-imidazo[4,5-c]quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DesaminoImiquimod
10mg
$ 130.00

TRC
DesaminoImiquimod
25mg
$ 265.00

Matrix Scientific
1-Isobutyl-1H-imidazo[4,5-c]quinoline 97%
10g
$ 2880.00

Matrix Scientific
1-Isobutyl-1H-imidazo[4,5-c]quinoline 97%
5g
$ 1782.00

CSNpharm
ImiquimodRelatedCompoundA
50mg
$ 50.00

Crysdot
1-Isobutyl-1H-imidazo[4,5-c]quinoline 95+%
5g
$ 800.00

Crysdot
1-Isobutyl-1H-imidazo[4,5-c]quinoline 95+%
10g
$ 1339.00

Crysdot
1-Isobutyl-1H-imidazo[4,5-c]quinoline 95+%
1g
$ 255.00

Crysdot
1-Isobutyl-1H-imidazo[4,5-c]quinoline 95+%
250mg
$ 102.00

Ambeed
1-Isobutyl-1H-imidazo[4,5-c]quinoline 95%
100mg
$ 110.00

Total 53 raw suppliers

Chemical Property of 1-Isobutyl-1H-imidazo[4,5-c]quinoline

Chemical Property:

Vapor Pressure:1.08E-06mmHg at 25°C
Melting Point:92-95℃
Boiling Point:402.6°C at 760 mmHg
PKA:5.34±0.30(Predicted)
Flash Point:197.3°C
PSA：30.71000
Density:1.17g/cm³
LogP:3.24050
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:225.126597491
Heavy Atom Count:17
Complexity:266

Purity/Quality:

97% ^*data from raw suppliers

DesaminoImiquimod ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2
Uses Desamino Imiquimod is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.

Technology Process of 1-Isobutyl-1H-imidazo[4,5-c]quinoline

There total 11 articles about 1-Isobutyl-1H-imidazo[4,5-c]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 99010-09-0
3-Amino-4-(2-methylpropylamino)-quinoline

: 64-18-6
formic acid

: 99010-24-9
1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

Guidance literature:: 3-Amino-4-(2-methylpropylamino)-quinoline; formic acid; at 110 - 115 ℃; for 8 - 10h;

With sodium hydroxide; In water; at 20 ℃; pH=10 - 11;

Reference yield: 15.0%

: 129377-66-8
3-amino-quinolin-4-ol; hydrochloride

: 78-81-9
isobutylamine

: 99010-24-9
1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

Guidance literature:: 3-amino-quinolin-4-ol; hydrochloride; N,N-dimethyl-formamide; With trichlorophosphate; In acetonitrile; at 20 ℃; for 21h;

isobutylamine; In acetonitrile; at 120 ℃; for 3h; Product distribution / selectivity;