isotonitazene

Base Information

• Chemical Name: isotonitazene
• CAS No.: 14188-81-9
• Molecular Formula: C₂₃H₃₀N₄O₃
• Molecular Weight: 410.516

Synonyms:

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Chemical Property of isotonitazene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of isotonitazene

There total 4 articles about isotonitazene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N’-(2,4-dinitrophenyl)-N,N-diethylethane-1,2-diamine (56223-91-7) → isotonitazene (14188-81-9)

Guidance literature:

Multi-step reaction with 2 steps

1: diammonium sulfide / ethanol; water / Reflux

2: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane

With diammonium sulfide; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In ethanol; dichloromethane; water;

DOI:10.1021/acschemneuro.1c00064

Reference yield:

N,N-diethylethylenediamine (100-36-7) → isotonitazene (14188-81-9)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol / Reflux

2: diammonium sulfide / ethanol; water / Reflux

3: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane

With diammonium sulfide; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In ethanol; dichloromethane; water;

DOI:10.1021/acschemneuro.1c00064

Reference yield:

4-hydroxyphenylacetic acid isopropyl ether (55784-07-1) + N(1)-(2-(diethylamino)ethyl)-4-nitrobenzene-1,2-diamine (5099-39-8) → isotonitazene (14188-81-9)

Guidance literature:

With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In dichloromethane;

DOI:10.1021/acschemneuro.1c00064

upstream raw materials:

N,N-diethylethylenediamine

N’-(2,4-dinitrophenyl)-N,N-diethylethane-1,2-diamine

4-hydroxyphenylacetic acid isopropyl ether

N⁽¹⁾-(2-(diethylamino)ethyl)-4-nitrobenzene-1,2-diamine