55784-07-1

Upstream product

• 55784-02-6 4-[(4-isopropoxy-phenyl)-thioacetyl]-morpholine 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 29056-05-1 methyl 2-(4-isopropoxyphenyl)acetate 
• 67-63-0 isopropyl alcohol 
• 156-38-7 4-hydroxyphenylacetate 
• 75-26-3 isopropyl bromide 

Downstream Products

• 587870-65-3 α-(p-isopropoxyphenyl)-p-isopropoxycinnamic acid 
• 1409950-43-1 1,7-difluoro-3-(4-isopropoxyphenyl)-6-methoxyisoquinoline 
• 1409950-45-3 (E)-3-(4-fluoro-3-methoxyphenyl)-2-(4-isopropoxyphenyl)acryloyl azide 
• 1409950-46-4 7-fluoro-3-(4-isopropoxyphenyl)-6-methoxyisoquinolin-1-ol 
• 1409950-47-5 1-chloro-7-fluoro-3-(4-isopropoxyphenyl)-6-methoxyisoquinoline 
• 1409950-44-2 (E)-3-(4-fluoro-3-methoxyphenyl)-2-(4-isopropoxyphenyl)acrylic acid 
• 14188-81-9 isotonitazene 
• 86817-78-9 2-(p-isopropoxyphenyl)ethyl methyl ether 
• 587870-67-5 (E)-1-(3,5-di-isopropoxyphenyl)-2-(4-isopropoxyphenyl)ethene 
• 587870-59-5 cis-3,4',5-triisopropoxystilbene 
• 61434-67-1 cis-resveratrol 
• 148788-27-6 α-(p-hydroxyphenyl)-p-hydroxycinnamic acid 
• 6628-41-7 α-(p-hydroxyphenyl)cinnamic acid 
• 501-36-0 (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol 

Relevant academic research and scientific papers

Hepatitis C virus inhibitors

Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Hepatitis C Virus Inhibitors

Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Total synthesis of (±)-armepavines and (±)-nuciferines from (2-nitroethenyl)benzene derivatives

A concise route to armepavine 1 and nuciferine 2 and 3, which can be isolated from the leaves of Nelumbo nucifera (Nymphaceae), has been achieved in which the longest linear sequence is only six steps from commercially available benzaldehyde in 28%, 21%, and 20% overall yield, respectively. The key transformations in the synthesis are the radical cyclization of aryl bromide with Bu3SnH and the Pictet-Spengler reaction of N-substituted amine with aldehyde. Copyright Taylor & Francis Group, LLC.

Novel benzimidazole derivatives as selective CB2 agonists

The preparation and evaluation of a novel class of CB2 agonists based on a benzimidazole moiety are reported. They showed binding affinities up to 1 nM towards the CB2 receptor with partial to full agonist potencies. They also demonstrated good to excellent selectivity (>1000-fold) over the CB1 receptor.

A-[(E)-2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPTHALENYL)-1-PROPENYL]BENZOIC ACID ANALOGS AND METHOD OF MANUFACTURE AND AND USE THEREOF

Analogs of 4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthalenyl)-1 - propenyl]benzoic acid and methods of manufacture and use thereof, such as for use in cancer prevention and treatment.

A re-investigation of resveratrol synthesis by Perkins reaction. Application to the synthesis of aryl cinnamic acids

A re-investigation of resveratrol synthesis by Perkins reaction allowed to improve this method and to determine the configuration of the intermediates. The results were applied to the synthesis of several aryl cinnamic acids for biological evaluation.

N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECPTOR AGENTS

Disclosed herein are compounds of Formula I, or a pharmaceutically acceptable salt, amide, ester, or prodrug thereof. Also disclosed are methods of inhibiting an activity of a monoamine receptor comprising contacting the monoamine receptor or a system containing the monoamine receptor with an effective amount of one or more of the compounds of Formula I. Disclosed are also methods of inhibiting an activation of a monoamine receptor comprising contacting the monoamine receptor or a system containing the monoamine receptor with an effective amount of one or more of the compounds of Formula I. Furthermore, methods of treating psychotic disease using a compound of Formula I are disclosed.

Polymer-Supported Mitsunobu Ether Formation and its Use in Combinatorial Chemistry

Aromatic hydroxy acids have been attached to a polymeric solid support and the phenolic hydroxy groups have been reacted with a variety of primary and secondary alcohols under the conditions of the Mitsunobu reaction (triphenylphosphine and diethyl azodicarboxylate) in tetrahydrofuran.In most cases the reaction provided a nearly quantitative yield of alkyl aryl ethers, as determined after cleaving theproduct from the resin.To demonstrate that the polymer-supported Mitsunobu reaction is useful for combinatorial library synthesis, we synthesized a number of model compounds and a simple three randomization step library composed of 4,200 different compounds.

Synthetic Approaches to C-18 Oxygenated Aspidosperma Alkaloids via Organoiron Complexes

An improved synthesis of (+/-)-limaspermine intermediate (3b), starting from tricarbonyl-1-4-η-iron (2c), is described.