2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester
CAS No.:189130-19-6
Molecular Formula:C₃₉H₅₄O₁₂
Molecular Weight:714.851
Hs Code.:

2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester

Synonyms:

Suppliers and Price of 2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester

There total 7 articles about 2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 189130-18-5
2,2-Dimethyl-propionic acid (1R,2R,3S,4S,6R)-1-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-4-(tert-butyl-dimethyl-silanyloxy)-3-(2,2-dimethyl-propionyloxymethyl)-6-(1-ethoxy-ethoxy)-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl ester

: 189130-19-6
2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester

Guidance literature:: With zinc dibromide; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1016/S0040-4039(97)00454-1

Reference yield:

: 3282-30-2
pivaloyl chloride

: 189130-19-6
2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 12 h / 5 °C

2: 96 percent / PPTS / CH₂Cl₂ / 3 h / Ambient temperature

3: ZnBr₂ / CH₂Cl₂ / 1 h / 0 °C

With pyridinium p-toluenesulfonate; zinc dibromide; In dichloromethane;
DOI:10.1016/S0040-4039(97)00454-1

Reference yield:

: 189130-14-1
(1S,4S)-1-[(S)-2,2-Bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-4-(tert-butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid dimethyl ester

: 189130-19-6
2,2-Dimethyl-propionic acid (1R,2R,3R,6S)-2-[(S)-2,2-bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-6-(2,2-dimethyl-propionyloxymethyl)-3-(1-ethoxy-ethoxy)-2-hydroxy-5-oxo-cyclohexylmethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: Mg / methanol / 2 h / 0 °C

2: I₂, AgOCOCF₃ / 1,2-dimethoxy-ethane / 12 h

3: 60 percent / LiAlH₄ / diethyl ether / 3 h / Heating

4: 12 h / 5 °C

5: 96 percent / PPTS / CH₂Cl₂ / 3 h / Ambient temperature

6: ZnBr₂ / CH₂Cl₂ / 1 h / 0 °C

With lithium aluminium tetrahydride; iodine; silver trifluoroacetate; pyridinium p-toluenesulfonate; magnesium; zinc dibromide; In methanol; 1,2-dimethoxyethane; diethyl ether; dichloromethane;
DOI:10.1016/S0040-4039(97)00454-1