2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetic acid lithium salt

Base Information

• Chemical Name: 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetic acid lithium salt
• CAS No.: 1097726-73-2
• Molecular Formula: C₂₅H₂₉N₄O₄*Li
• Molecular Weight: 456.471
• Mol file: 1097726-73-2.mol

Synonyms:

Chemical Property of 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetic acid lithium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetic acid lithium salt

There total 1 articles about 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetic acid lithium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetate (1097726-72-1) → 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetic acid lithium salt (1097726-73-2)

Guidance literature:

With lithium hydroxide; In methanol; for 48h;

DOI:10.1039/b806391e

Reference yield: 77.0%

sodium hexaflorophosphate + 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetic acid lithium salt (1097726-73-2) + zinc diacetate (557-34-6) → [Zn2([2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetate(2-)])(CH3COO)](PF6)*H2O

Guidance literature:

In methanol; to soln. Li salt ligand in MeOH soln. Zn(OAc)2 in MeOH was added dropwise and refluxed for 30 min, cooled to room temp., soln. NaPF6 in MeOH wasadded and left at room temp.; slow evapn., ppt. was filtered; elem. anal.;

DOI:10.1039/b806391e

Reference yield:

methanol (67-56-1) + sodium hexaflorophosphate + 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetic acid lithium salt (1097726-73-2) + zinc diacetate (557-34-6) → Li[Zn2([2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetate(2-)])]4(PO4)2(PF6)3*CH3OH

Guidance literature:

In methanol; to soln. Li salt ligand in MeOH soln. Zn(OAc)2 in MeOH was added dropwise and refluxed for 30 min, cooled to room temp., soln. NaPF6 in MeOH wasadded and left at room temp. for 4 days;

DOI:10.1039/b806391e

upstream raw materials:

ethyl 2-((2-hydroxy-3-(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzyl)(pyridin-2-ylmethyl)amino)acetate