E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle

Base Information

• Chemical Name: E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle
• CAS No.: 20414-93-1
• Molecular Formula: C₁₃H₁₄O₂
• Molecular Weight: 202.253
• Mol file: 20414-93-1.mol

Synonyms:

Chemical Property of E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle

There total 19 articles about E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 2-(diethoxyphosphoryl)propanoate (29668-62-0) + 3-phenyl-propenal (104-55-2) → E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle (20414-93-1,20414-96-4,20430-17-5,89996-94-1,116760-88-4,20414-95-3)

Guidance literature:

methyl 2-(diethoxyphosphoryl)propanoate; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h; Inert atmosphere;

3-phenyl-propenal; In tetrahydrofuran; hexane; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.0c00915

Reference yield: 85.0%

methanol (67-56-1) + (E)-4-Methyl-5,5-bis-methylsulfanyl-1-phenyl-penta-2,4-dien-1-ol → E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle (20414-93-1,20414-96-4,20430-17-5,89996-94-1,116760-88-4,20414-95-3)

Guidance literature:

With boron trifluoride diethyl etherate; for 16h; Heating;

Reference yield: 76.0%

[(2Z,4E)-2-methoxycarbonyl-5-phenyl-2,4-pentadienyl]triphenylphosphonium bromide (1367876-33-2) → E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle (20414-93-1,20414-96-4,20430-17-5,89996-94-1,116760-88-4,20414-95-3)

Guidance literature:

With water; sodium hydrogencarbonate; at 100 - 105 ℃; for 0.333333h; diastereoselective reaction; Microwave irradiation;

DOI:10.1002/hc.21001

upstream raw materials:

methanol

2-methyl-5-phenyl-penta-2,4-dienoic acid

Methyl 2-bromopropionate

3-phenyl-propenal

Downstream raw materials:

(2E,4E)-2-methyl-5-phenyl-2,4-pentadienoic acid