2-benzyloxy-3-chlorobenzoic anhydride

Base Information

• Chemical Name: 2-benzyloxy-3-chlorobenzoic anhydride
• CAS No.: 80352-54-1
• Molecular Formula: C₂₈H₂₀Cl₂O₅
• Molecular Weight: 507.37
• Mol file: 80352-54-1.mol

Synonyms:

Chemical Property of 2-benzyloxy-3-chlorobenzoic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzyloxy-3-chlorobenzoic anhydride

There total 4 articles about 2-benzyloxy-3-chlorobenzoic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-benzyloxy-3-chlorobenzoic acid (80352-53-0) → 2-benzyloxy-3-chlorobenzoic anhydride (80352-54-1)

Guidance literature:

With pyridine; thionyl chloride; In benzene; for 14h;

Reference yield:

3-chlorosalicylaldehyde (1927-94-2) → 2-benzyloxy-3-chlorobenzoic anhydride (80352-54-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 66.6 percent / K₂CO₃ / dimethylformamide / 1 h / Heating

2: 84 percent / silver nitrate, 40 percent NaOH / H₂O / 0.5 h / Heating

3: 73 percent / pyridine, thionyl chloride / benzene / 14 h

With pyridine; sodium hydroxide; thionyl chloride; potassium carbonate; silver nitrate; In water; N,N-dimethyl-formamide; benzene;

Reference yield:

benzyl chloride (100-44-7) → 2-benzyloxy-3-chlorobenzoic anhydride (80352-54-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 66.6 percent / K₂CO₃ / dimethylformamide / 1 h / Heating

2: 84 percent / silver nitrate, 40 percent NaOH / H₂O / 0.5 h / Heating

3: 73 percent / pyridine, thionyl chloride / benzene / 14 h

With pyridine; sodium hydroxide; thionyl chloride; potassium carbonate; silver nitrate; In water; N,N-dimethyl-formamide; benzene;

upstream raw materials:

2-benzyloxy-3-chlorobenzoic acid

3-chlorosalicylaldehyde

benzyl chloride

2-(benzyloxy)-3-chlorobenzaldehyde

Downstream raw materials:

3'-chloro-2'-benzyloxy-5,7-dihydroxy-3-methoxyflavone

3'-chloro-2'-benzyloxy-5-hydroxy-3,7,8-trimethoxyflavone

3'-chloro-2'-benzyloxy-5,7,8-trihydroxy-3-methoxyflavone

chlorflavonin