Technology Process of 3'-chloro-2'-benzyloxy-5,7-dihydroxy-3-methoxyflavone
There total 5 articles about 3'-chloro-2'-benzyloxy-5,7-dihydroxy-3-methoxyflavone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 66.6 percent / K2CO3 / dimethylformamide / 1 h / Heating
2: 84 percent / silver nitrate, 40 percent NaOH / H2O / 0.5 h / Heating
3: 73 percent / pyridine, thionyl chloride / benzene / 14 h
4: 1.) triethylamine; 2.) 60 percent KOH / 1.) 175 deg C, 1 h; 2.) methanol, 30 min, reflux
With
pyridine; potassium hydroxide; sodium hydroxide; thionyl chloride; potassium carbonate; silver nitrate; triethylamine;
In
water; N,N-dimethyl-formamide; benzene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 66.6 percent / K2CO3 / dimethylformamide / 1 h / Heating
2: 84 percent / silver nitrate, 40 percent NaOH / H2O / 0.5 h / Heating
3: 73 percent / pyridine, thionyl chloride / benzene / 14 h
4: 1.) triethylamine; 2.) 60 percent KOH / 1.) 175 deg C, 1 h; 2.) methanol, 30 min, reflux
With
pyridine; potassium hydroxide; sodium hydroxide; thionyl chloride; potassium carbonate; silver nitrate; triethylamine;
In
water; N,N-dimethyl-formamide; benzene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 84 percent / silver nitrate, 40 percent NaOH / H2O / 0.5 h / Heating
2: 73 percent / pyridine, thionyl chloride / benzene / 14 h
3: 1.) triethylamine; 2.) 60 percent KOH / 1.) 175 deg C, 1 h; 2.) methanol, 30 min, reflux
With
pyridine; potassium hydroxide; sodium hydroxide; thionyl chloride; silver nitrate; triethylamine;
In
water; benzene;
