methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosid>onate

Base Information

• Chemical Name: methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosid>onate
• CAS No.: 125532-26-5
• Molecular Formula: C₂₇H₃₃N₅O₁₂S
• Molecular Weight: 651.651
• Mol file: 125532-26-5.mol

Synonyms:

Chemical Property of methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosid>onate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosid>onate

There total 2 articles about methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosid>onate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

S,S-bis(1-phenyl-1H-tetrazol-5-yl) dithiocarbonate (32276-00-9) + methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-β-D-galacto-2-nonulopyranosonate (20298-34-4,84380-10-9) → 1-phenyl-1H-tetrazol-5-yl(5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-2-nonulopyranoside)thionate (125532-28-7,130792-22-2) + methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-β-D-galacto-2-nonulopyranosid>onate (125532-26-5,125532-27-6) + methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosid>onate (125532-26-5,125532-27-6)

Guidance literature:

With dmap; In acetonitrile; for 24h; Ambient temperature;

DOI:10.1016/0008-6215(90)80045-5

Reference yield: 28.0%

S,S-bis(1-phenyl-1H-tetrazol-5-yl) dithiocarbonate (32276-00-9) + methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-β-D-galacto-2-nonulopyranosonate (20298-34-4,84380-10-9) → 1-phenyl-1H-tetrazol-5-yl(5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-2-nonulopyranoside)thionate (125532-28-7,130792-22-2) + methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-β-D-galacto-2-nonulopyranosid>onate (125532-26-5,125532-27-6) + methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosid>onate (125532-26-5,125532-27-6)

Guidance literature:

With dmap; In acetonitrile; for 24h; Ambient temperature;

DOI:10.1016/0008-6215(90)80045-5

Reference yield: 56.0%

methanol (67-56-1) + methyl <1-phenyl-1H-tetrazol-5-yl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosid>onate (125532-26-5,125532-27-6) → methyl N-acetyl-4,7,8,9-tetra-O-acetyl-2-deoxy-2,3-dehydro-D-neuraminate (73960-72-2,78918-92-0,108812-69-7,108812-70-0,108812-71-1) + methyl (methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-nonulopyranosid)onate (41521-03-3,56323-64-9,73208-80-7,88547-02-8,99395-95-6,99395-96-7,99395-97-8,140385-82-6,140385-83-7,140385-84-8)

Guidance literature:

With 4 A molecular sieve; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; In acetonitrile; for 24h;

DOI:10.1016/0008-6215(90)80045-5

upstream raw materials:

S,S-bis(1-phenyl-1H-tetrazol-5-yl) dithiocarbonate

methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-β-D-galacto-2-nonulopyranosonate

Downstream raw materials:

methyl N-acetyl-4,7,8,9-tetra-O-acetyl-2-deoxy-2,3-dehydro-D-neuraminate

methyl (methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-nonulopyranosid)onate

C₆₇H₇₇NO₂₂