8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline

Base Information

Chemical Name:8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline
CAS No.:1220694-87-0
Molecular Formula:C₁₀H₁₂BrNO
Molecular Weight:242.115
Hs Code.:
Mol file:1220694-87-0.mol

Synonyms:

Suppliers and Price of 8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
8-Bromo-6-methoxy-1,2,3,4-tetrahydroisoquinolinehydrochloride 95+%
1g
$ 412.00

Chemenu
8-Bromo-6-methoxy-1,2,3,4-tetrahydroisoquinolinehydrochloride 95%
1g
$ 389.00

Total 5 raw suppliers

Chemical Property of 8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

8-Bromo-6-methoxy-1,2,3,4-tetrahydroisoquinolinehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline

There total 6 articles about 8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 64-18-6
formic acid

: 262450-67-9
2-(3-bromo-5-methoxyphenyl)ethylamine

: 1220694-87-0
8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: at 50 ℃; Inert atmosphere;

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 262450-67-9
2-(3-bromo-5-methoxyphenyl)ethylamine

: 1220694-87-0
8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: formaldehyd; 2-(3-bromo-5-methoxyphenyl)ethylamine; In formic acid; at 50 ℃; for 13.5h;

With sodium hydroxide; In dichloromethane; water;

Reference yield:

: 74204-00-5
3-bromo-5-methylphenol

: 1220694-87-0
8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 5 steps

1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C

2: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 12 h / Reflux

3: tetrabutyl ammonium fluoride / acetonitrile / 12.5 h / 20 °C

4: nickel; hydrogen; ammonium hydroxide / methanol / 5 h / 20 °C / 2585.81 Torr

5: 50 °C / Inert atmosphere

With ammonium hydroxide; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; hydrogen; nickel; potassium carbonate; In methanol; tetrachloromethane; N,N-dimethyl-formamide; acetonitrile;