(1s,3s)-3-fluoro-3-methylcyclobutanecarboxylic acid

Base Information

Chemical Name:(1s,3s)-3-fluoro-3-methylcyclobutanecarboxylic acid
CAS No.:1455037-45-2
Molecular Formula:C₆H₉FO₂
Molecular Weight:132.135
Hs Code.:2916200090
Mol file:1455037-45-2.mol

Synonyms:

Suppliers and Price of (1s,3s)-3-fluoro-3-methylcyclobutanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(1s,3s)-3-Fluoro-3-methylcyclobutanecarboxylic acid 95%
100mg
$ 444.00

Matrix Scientific
(1s,3s)-3-Fluoro-3-methylcyclobutanecarboxylic acid 95%
500mg
$ 1273.00

American Custom Chemicals Corporation
CIS-3-FLUORO-3-METHYLCYCLOBUTANE-1-CARBOXYLIC ACID 95.00%
5MG
$ 455.29

Activate Scientific
cis-3-Fluoro-3-methylcyclobutane-1-carboxylic acid 95+%
1 g
$ 1397.00

Activate Scientific
cis-3-Fluoro-3-methylcyclobutane-1-carboxylic acid 95+%
250 mg
$ 650.00

Activate Scientific
cis-3-Fluoro-3-methylcyclobutane-1-carboxylic acid 95+%
100 mg
$ 305.00

Total 3 raw suppliers

Chemical Property of (1s,3s)-3-fluoro-3-methylcyclobutanecarboxylic acid

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(1s,3s)-3-Fluoro-3-methylcyclobutanecarboxylic acid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1s,3s)-3-fluoro-3-methylcyclobutanecarboxylic acid

There total 5 articles about (1s,3s)-3-fluoro-3-methylcyclobutanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1455037-44-1
trans-benzyl 3-fluoro-3-methylcyclobutanecarboxylate

: 1455037-45-2,1613330-60-1
3-methyl-cis-3-fluorocyclobutanecarboxylic acid

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; under 760.051 Torr;

Reference yield:

: 23761-23-1
3-oxocyclobutanecarboxylic acid

: 1455037-45-2,1613330-60-1
3-methyl-cis-3-fluorocyclobutanecarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: 1,1'-carbonyldiimidazole / dichloromethane / 2 h / 20 °C

1.2: 16 h / 20 °C

2.1: tetrahydrofuran; diethyl ether / 0.5 h / -78 °C

3.1: diethylamino-sulfur trifluoride / dichloromethane / -78 - 20 °C / Inert atmosphere

4.1: palladium 10% on activated carbon; hydrogen / methanol / 760.05 Torr

With diethylamino-sulfur trifluoride; palladium 10% on activated carbon; hydrogen; 1,1'-carbonyldiimidazole; In tetrahydrofuran; methanol; diethyl ether; dichloromethane;

Reference yield:

: 198995-91-4
benzyl 3-oxocyclobutane-1-carboxylate

: 1455037-45-2,1613330-60-1
3-methyl-cis-3-fluorocyclobutanecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran; diethyl ether / 0.5 h / -78 °C

2: diethylamino-sulfur trifluoride / dichloromethane / -78 - 20 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen / methanol / 760.05 Torr

With diethylamino-sulfur trifluoride; palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; methanol; diethyl ether; dichloromethane;