[4-[[[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-methyl]amino]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester

Base Information

Chemical Name:[4-[[[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-methyl]amino]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester
CAS No.:301672-84-4
Molecular Formula:C₃₀H₄₄ClN₃O₃
Molecular Weight:530.151
Hs Code.:

[4-[[[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-methyl]amino]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester

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Chemical Property of [4-[[[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-methyl]amino]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester

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Technology Process of [4-[[[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-methyl]amino]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester

There total 3 articles about [4-[[[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-methyl]amino]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 195314-59-1
tert-butyl (4-aminocyclohexyl)carbamate

: 301672-81-1
2-chloro-5-formyl-N-(tricyclo[3.3.1.1^3,7]dec-1-ylmethyl)benzamide

: 107-06-2,52399-93-6
1,2-dichloro-ethane

: 301672-84-4
[4-[[[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-methyl]amino]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester

Guidance literature:: With sodium tris(acetoxy)borohydride;

Reference yield:

: 301672-80-0
5-bromo-2-chloro-N-(tricyclo[3.3.1.1^3,7]dec-1-ylmethyl)benzamide

: 301672-84-4
[4-[[[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-methyl]amino]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: methyllithium; tert.-butyl lithium / tetrahydrofuran; N-methyl-acetamide; diethyl ether; pentane

2: sodium tris(acetoxy)borohydride

With methyllithium; tert.-butyl lithium; sodium tris(acetoxy)borohydride; In tetrahydrofuran; N-methyl-acetamide; diethyl ether; pentane;

Reference yield:

: 17768-41-1
adamantylmethylamine

: 301672-84-4
[4-[[[4-chloro-3-[[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]carbonyl]phenyl]-methyl]amino]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / N-methyl-acetamide; dichloromethane

2: methyllithium; tert.-butyl lithium / tetrahydrofuran; N-methyl-acetamide; diethyl ether; pentane

3: sodium tris(acetoxy)borohydride

With methyllithium; tert.-butyl lithium; sodium tris(acetoxy)borohydride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N-methyl-acetamide; diethyl ether; dichloromethane; pentane;