N-TERT-BUTYL-OXALAMIC ACID ETHYL ESTER

Base Information

• Chemical Name: N-TERT-BUTYL-OXALAMIC ACID ETHYL ESTER
• CAS No.: 87034-69-3
• Molecular Formula: C₈H₁₅NO₃
• Molecular Weight: 173.212
• Mol file: 87034-69-3.mol

Synonyms:

Chemical Property of N-TERT-BUTYL-OXALAMIC ACID ETHYL ESTER

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Acetic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-TERT-BUTYL-OXALAMIC ACID ETHYL ESTER

There total 2 articles about N-TERT-BUTYL-OXALAMIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

Ethyl oxalyl chloride (4755-77-5) + tert-butylamine (75-64-9) → N-tert-butyloxanillic acid ethyl ester (87034-69-3)

Guidance literature:

In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jo1017603

Reference yield:

tert-butylamine (75-64-9) + oxalic acid diethyl ester (95-92-1) → N-tert-butyloxanillic acid ethyl ester (87034-69-3)

Guidance literature:

DOI:10.1002/ardp.19602930214

Reference yield: 90.0%

N-tert-butyloxanillic acid ethyl ester (87034-69-3) + 2-amino-phenol (95-55-6) → N-(tert-butyl)-N‘-(2-hydroxyphenyl)-oxalamide

Guidance literature:

With triethylamine; In toluene; Reflux; Inert atmosphere;

DOI:10.1021/acs.organomet.9b00481

upstream raw materials:

tert-butylamine

oxalic acid diethyl ester

Ethyl oxalyl chloride

Downstream raw materials:

2-(tert-butylamino)-2-oxoacetic acid

C₁₂H₁₆N₂O₂

C₁₃H₂₂N₄O