trans-2,3-epoxy-3-(2-propanyl)-1-phenyl-1-propanone

Base Information

• Chemical Name: trans-2,3-epoxy-3-(2-propanyl)-1-phenyl-1-propanone
• CAS No.: 84034-01-5
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.242
• Mol file: 84034-01-5.mol

Synonyms:

Chemical Property of trans-2,3-epoxy-3-(2-propanyl)-1-phenyl-1-propanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-2,3-epoxy-3-(2-propanyl)-1-phenyl-1-propanone

There total 7 articles about trans-2,3-epoxy-3-(2-propanyl)-1-phenyl-1-propanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-phenyl-4-methyl-2-penten-1-one (7316-69-0,36597-08-7,56438-83-6) → trans-2,3-epoxy-3-(2-propanyl)-1-phenyl-1-propanone (84034-01-5,84034-02-6)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; In methanol;

DOI:10.1021/jo00004a052

Reference yield: 81.0%

1-chloroacetophenone (532-27-4,108321-66-0,164322-25-2) + isobutyraldehyde (78-84-2) → trans-2,3-epoxy-3-(2-propanyl)-1-phenyl-1-propanone (84034-01-5,84034-02-6)

Guidance literature:

1-chloroacetophenone; isobutyraldehyde; With sodium dodecyl-sulfate; In water; at 0 ℃; for 0.25h;

With lithium hydroxide; In water; at 0 ℃; for 0.25h; stereoselective reaction;

DOI:10.1021/jo501500v

Reference yield: 60.0%

(E)-4-methyl-1-phenyl-2-penten-1-one (36597-08-7) → trans-2,3-epoxy-3-(2-propanyl)-1-phenyl-1-propanone (84034-01-5,84034-02-6)

Guidance literature:

With lithium hydroxide; dihydrogen peroxide; Merrifield resin bound DABCO chloride salt; In diethyl ether; at 20 ℃; for 30h;

upstream raw materials:

1-phenyl-4-methyl-2-penten-1-one

isobutyraldehyde

α-bromoacetophenone

(E)-4-methyl-1-phenyl-2-penten-1-one

Downstream raw materials:

4-methyl-1-phenyl-pentane-1,3-dione

3-hydroxy-4-methyl-1-phenylpentan-1-one

1-phenyl-4-methyl-2-penten-1-one