C₁₀₄H₁₄₀N₁₆O₂₀

Base Information

• Chemical Name: C₁₀₄H₁₄₀N₁₆O₂₀
• CAS No.: 1008365-07-8
• Molecular Formula: C₁₀₄H₁₄₀N₁₆O₂₀
• Molecular Weight: 1934.35
• Mol file: 1008365-07-8.mol

Synonyms:

Chemical Property of C₁₀₄H₁₄₀N₁₆O₂₀

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₁₀₄H₁₄₀N₁₆O₂₀

There total 1 articles about C₁₀₄H₁₄₀N₁₆O₂₀ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(tert-butoxycarbonyl)-L-proline (15761-39-4,59433-50-0) + t-Boc-L-valine (13734-41-3) + N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) + Boc-Orn(Z)-OH (2480-93-5) + Boc-D-Phe-OH (18942-49-9) + (R)-6-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoic acid (55878-47-2) → C104H140N16O20 (1008365-07-8)

Guidance literature:

N-tert-butoxycarbonyl-L-leucine; With dicyclohexyl-carbodiimide; In dichloromethane; for 24h; solid phase reaction;

With trifluoroacetic acid; In dichloromethane; for 0.5h; solid phase reaction;

1-(tert-butoxycarbonyl)-L-proline; t-Boc-L-valine; N-tert-butoxycarbonyl-L-leucine; Boc-Orn(Z)-OH; Boc-D-Phe-OH; (R)-6-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoic acid; Further stages;

DOI:10.1016/j.bmcl.2009.03.133

Reference yield:

C104H140N16O20 (1008365-07-8) → [D-Lys(6,6')]-gratisin tetrahydrochloride

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In 1,4-dioxane; methanol; water; for 48h;

DOI:10.1016/j.bmcl.2009.03.133

upstream raw materials:

1-(tert-butoxycarbonyl)-L-proline

t-Boc-L-valine

N-tert-butoxycarbonyl-L-leucine

Boc-Orn(Z)-OH