t-Boc-Aminoxy-PEG3-Azide

Base Information

Chemical Name:t-Boc-Aminoxy-PEG3-Azide
CAS No.:1235514-15-4
Molecular Formula:C₁₃H₂₆N₄O₆
Molecular Weight:334.373
Hs Code.:

Synonyms:

Suppliers and Price of t-Boc-Aminoxy-PEG3-Azide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
t-Boc-aminooxy-peg3-azide
50mg
$ 330.00

TRC
t-Boc-aminooxy-peg3-azide
5mg
$ 65.00

BroadPharm
t-Boc-Aminooxy-PEG3-azide 98%
250 MG
$ 480.00

BroadPharm
t-Boc-Aminooxy-PEG3-azide 98%
100 MG
$ 280.00

BroadPharm
t-Boc-Aminooxy-PEG3-azide 98%
500 MG
$ 750.00

Apolloscientific
t-Boc-Aminoxy-PEG3-Azide
100mg
$ 546.00

Total 8 raw suppliers

Chemical Property of t-Boc-Aminoxy-PEG3-Azide

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

t-Boc-aminooxy-peg3-azide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description t-Boc-Aminooxy-PEG3-azide is a click chemistry reagent containing a t-Boc-aminooxy group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The protected aminooxy can be deprotected under mild acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.

Technology Process of t-Boc-Aminoxy-PEG3-Azide

There total 5 articles about t-Boc-Aminoxy-PEG3-Azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 36016-38-3
tert-Butyl N-hydroxycarbamate

: 134179-43-4
11-azide-1-{(methylsulfonyl)oxy}-3,6,9-trioxaundecane

: 1235514-15-4
tert-butyl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxycarbamate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran;
DOI:10.1016/j.tetlet.2010.04.078

Reference yield: 60.0%

: 36016-38-3
tert-Butyl N-hydroxycarbamate

: 168640-82-2
11-azido-3,6,9-trioxa-undecanyl p-toluenesulfonate

: 1235514-15-4
tert-butyl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxycarbamate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; for 72h;

Reference yield:

: 112-60-7
Tetraethylene glycol

: 1235514-15-4
tert-butyl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxycarbamate

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 16 h / 20 °C

2: sodium azide / N,N-dimethyl-formamide / 16 h / 80 °C

3: triethylamine / dichloromethane / 16 h / 20 °C

4: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 72 h / 20 °C

With sodium azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; In dichloromethane; N,N-dimethyl-formamide;