2-(3,5-dimethyl-1H-pyrazol-4-yl)aniline

Base Information

• Chemical Name: 2-(3,5-dimethyl-1H-pyrazol-4-yl)aniline
• CAS No.: 103858-98-6
• Molecular Formula: C₁₁H₁₃N₃
• Molecular Weight: 187.244
• European Community (EC) Number: 842-002-1
• Mol file: 103858-98-6.mol

Synonyms:2-(3,5-dimethyl-1H-pyrazol-4-yl)aniline;103858-98-6;AKOS000141002;MCULE-6477125743;CS-0249286;EN300-43004;Z316121102;K31

Chemical Property of 2-(3,5-dimethyl-1H-pyrazol-4-yl)aniline

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 187.110947427
• Heavy Atom Count: 14
• Complexity: 195

Purity/Quality:

2-(3,5-Dimethyl-1H-pyrazol-4-yl)aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(C(=NN1)C)C2=CC=CC=C2N

Technology Process of 2-(3,5-dimethyl-1H-pyrazol-4-yl)aniline

There total 2 articles about 2-(3,5-dimethyl-1H-pyrazol-4-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-acetyl-2-methylindole (22582-52-1) → 2-(3,5-dimethyl-1(2)H-pyrazol-4-yl)-aniline (103858-98-6)

Guidance literature:

With ethanol; hydrazine hydrate; unter Druck;

Reference yield:

3-acetyl-2-methylindole (22582-52-1) + hydrazine hydrate (7803-57-8,79785-97-0) + ethylene glycol (107-21-1) → bis-[1-(2-methyl-indol-3-yl)-ethylidene]-hydrazine (102314-22-7) + 2-(3,5-dimethyl-1(2)H-pyrazol-4-yl)-aniline (103858-98-6)

Guidance literature:

at 120 - 160 ℃;

Reference yield:

2-(3,5-dimethyl-1(2)H-pyrazol-4-yl)-aniline (103858-98-6) → 3,5-dimethyl-4-phenyl-1H-pyrazole (4345-49-7)

Guidance literature:

With hydrogenchloride; sodium nitrite; anschliessend Behandeln mit wss. H₃PO₂;

upstream raw materials:

3-acetyl-2-methylindole

hydrazine hydrate

ethylene glycol

Downstream raw materials:

3,5-dimethyl-4-phenyl-1H-pyrazole