3-Bromopropyltrimethylsilane

Base Information

• Chemical Name: 3-Bromopropyltrimethylsilane
• CAS No.: 10545-34-3
• Molecular Formula: C6H15BrSi
• Molecular Weight: 195.175
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID10511339
• Nikkaji Number: J46.916E
• Wikidata: Q63398155
• Mol file: 10545-34-3.mol

Synonyms:3-Bromopropyltrimethylsilane;10545-34-3;3-bromopropyl(trimethyl)silane;(3-BROMOPROPYL)TRIMETHYLSILANE;3-(trimethylsilyl)propyl bromide;(3-Bromopropyl)(trimethyl)silane;3-trimethylsilyl-propyl bromide;SCHEMBL5672065;DTXSID10511339;NVEYOAXSXPSFHL-UHFFFAOYSA-N;EN300-674057;Q63398155

Chemical Property of 3-Bromopropyltrimethylsilane

Chemical Property:

• PSA: 0.00000
• LogP: 3.10960
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 194.01264
• Heavy Atom Count: 8
• Complexity: 56

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)CCCBr

Technology Process of 3-Bromopropyltrimethylsilane

There total 5 articles about 3-Bromopropyltrimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

3-trimethylsilyl-1-propanol (2917-47-7) → 3-(trimethylsilyl)propyl bromide (10545-34-3)

Guidance literature:

With PBr₃; In not given;

DOI:10.1021/ja01177a033

Reference yield:

3-trimethylsilyl-1-propanol (2917-47-7) + phosphorus tribromide (7789-60-8) → 3-(trimethylsilyl)propyl bromide (10545-34-3)

Guidance literature:

Reference yield:

3-(trimethylsilyl)propan-1-ol tosylate (88729-78-6) → 3-(trimethylsilyl)propyl bromide (10545-34-3)

Guidance literature:

With lithium bromide; In 1,2-dimethoxyethane; Heating;

DOI:10.1021/jo00180a041

upstream raw materials:

3-trimethylsilyl-1-propanol

(3-bromopropyl)trichlorosilane

methylmagnesium chloride

3-(trimethylsilyl)propan-1-ol tosylate

Downstream raw materials:

cyclopropane

9-Fluorenol

9-<3-(trimethylsilyl)propyl>-9-fluorenol

4-[3-(trimethylsilyl)propylamino]benzoic acid

Refernces

• 1、 Maercker, Adalbert,Eckers, Mechthild,Passlack, Michael. "CARBANIONEN-UMLAGERUNGEN DURCH INTRAMOLEKULARE 1,ω-PROTONVERSCHIEBUNG. II. ZUR REAKTIONSWEISE VON 3-, 4- UND 5-LITHIOALKYL-TRIMETHYLSILANEN". . p. 193 - 205. Retrieved 1980.
• 2、 -. "N-derivatives of 1-deoxy nojirimycin". . . Retrieved 2008/06/13.
• 3、 Urabe, Hirokazu,Kuwajima, Isao. "A Cyclopentanone Annulation via Intramolecular Acylation of Alkylsilanes". . p. 1140 - 1141. Retrieved 2007/10/02.