4-[(4-Aminophenyl)sulfonyl]-1,3,5-benzenetriol

Base Information

• Chemical Name: 4-[(4-Aminophenyl)sulfonyl]-1,3,5-benzenetriol
• CAS No.: 105456-65-3
• Molecular Formula: C12H11NO5S
• Molecular Weight: 281.28400
• Mol file: 105456-65-3.mol

Synonyms:(4-Amino-phenyl)-(2.4.6-trihydroxy-phenyl)-sulfon;2-(4-Amino-benzenesulfonyl)-benzene-1,3,5-triol;2-Sulfanilyl-phloroglucin;2-(4-Amino-phenylsulfon)-phloroglucin;

Chemical Property of 4-[(4-Aminophenyl)sulfonyl]-1,3,5-benzenetriol

Chemical Property:

• Melting Point: 209 - 210 °C (H2O)
• PSA: 129.23000
• LogP: 2.88040

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-[(4-Aminophenyl)sulfonyl]-1,3,5-benzenetriol

There total 6 articles about 4-[(4-Aminophenyl)sulfonyl]-1,3,5-benzenetriol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-nitro-benzenesulfonyl)-phloroglucinol (861015-12-5) → 2-sulfanilyl-phloroglucinol (105456-65-3)

Guidance literature:

With hydrogenchloride; iron;

DOI:10.1039/jr9450000468

Reference yield:

4-nitrobenzenesulfenyl chloride (937-32-6) → 2-sulfanilyl-phloroglucinol (105456-65-3)

Guidance literature:

Multi-step reaction with 5 steps

1: diethyl ether

2: sodium acetate

3: glacial acetic acid; acetic acid anhydride; aqueous H₂O₂

4: aq.-ethanolic sulfuric acid

5: iron; aq.-ethanolic hydrochloric acid

With hydrogenchloride; diethyl ether; sulfuric acid; dihydrogen peroxide; sodium acetate; acetic anhydride; iron; acetic acid;

DOI:10.1039/jr9450000468

Reference yield:

3,5-dihydroxyphenol (108-73-6) → 2-sulfanilyl-phloroglucinol (105456-65-3)

Guidance literature:

Multi-step reaction with 5 steps

1: diethyl ether

2: sodium acetate

3: glacial acetic acid; acetic acid anhydride; aqueous H₂O₂

4: aq.-ethanolic sulfuric acid

5: iron; aq.-ethanolic hydrochloric acid

With hydrogenchloride; diethyl ether; sulfuric acid; dihydrogen peroxide; sodium acetate; acetic anhydride; iron; acetic acid;

DOI:10.1039/jr9450000468

upstream raw materials:

2-(4-nitro-benzenesulfonyl)-phloroglucinol

4-nitrobenzenesulfenyl chloride

3,5-dihydroxyphenol

2-(4-nitro-phenylsulfanyl)-phloroglucinol