Technology Process of C27H39NO6
There total 4 articles about C27H39NO6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
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1583315-19-8
((3R,4S,5S,7R,11R,12R,E)-12-ethyl-3,5,7,11-tetramethyl-2,8-dioxo-1-oxacyclododec-9-en-4-yl) 2-((dimethylamino)methyl)benzoate
- Guidance literature:
-
With
nicotinamide adenine dinucleotide phosphate; glucose-6-phosphate dehydrogenase; PikCD50N-RhFRED;
In
aq. phosphate buffer;
at 30 ℃;
for 3h;
pH=7.3;
Overall yield = 77 %; regioselective reaction;
DOI:10.1021/ja5016052
- Guidance literature:
-
Multi-step reaction with 3 steps
1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1.5 h / 20 °C
2: triethylamine; dmap / dichloromethane / 12 h / 20 °C
3: PikCD50N-RhFRED; glucose-6-phosphate dehydrogenase; nicotinamide adenine dinucleotide phosphate / aq. phosphate buffer / 3 h / 30 °C / pH 7.3
With
nicotinamide adenine dinucleotide phosphate; dmap; glucose-6-phosphate dehydrogenase; oxalyl dichloride; PikCD50N-RhFRED; triethylamine; N,N-dimethyl-formamide;
In
aq. phosphate buffer; dichloromethane;
DOI:10.1021/ja5016052
- Guidance literature:
-
Multi-step reaction with 4 steps
1: water; ethanol / 12 h / 20 °C
2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1.5 h / 20 °C
3: triethylamine; dmap / dichloromethane / 12 h / 20 °C
4: PikCD50N-RhFRED; glucose-6-phosphate dehydrogenase; nicotinamide adenine dinucleotide phosphate / aq. phosphate buffer / 3 h / 30 °C / pH 7.3
With
nicotinamide adenine dinucleotide phosphate; dmap; glucose-6-phosphate dehydrogenase; oxalyl dichloride; PikCD50N-RhFRED; triethylamine; N,N-dimethyl-formamide;
In
aq. phosphate buffer; ethanol; dichloromethane; water;
DOI:10.1021/ja5016052