55741-01-0 Usage
Uses
Used in Pharmaceutical Industry:
2-Dimethylaminomethyl-benzoic acid is used as an active ingredient in pharmaceutical products for the treatment of respiratory conditions such as bronchitis and COPD. It is used for its antihistamine and mucolytic properties, which help in relaxing the muscles in the airways and thinning mucus, making it easier to breathe and facilitating the removal of mucus.
Used in Respiratory Treatment:
2-Dimethylaminomethyl-benzoic acid is used as a therapeutic agent in respiratory treatment to improve lung function and alleviate symptoms of respiratory conditions. Its ability to relax airway muscles and thin mucus contributes to better breathing and overall respiratory health.
Used in Inhalation Therapy:
2-Dimethylaminomethyl-benzoic acid is used in inhalation therapy as a means to deliver the compound directly to the respiratory system. This method of administration allows for targeted treatment of respiratory conditions, maximizing the compound's effectiveness and minimizing potential side effects.
Used in Oral Medication:
2-Dimethylaminomethyl-benzoic acid is also used in oral medication formulations, providing an alternative route of administration for patients who may not be able to use inhalation therapy or for whom this method is not suitable. The oral route ensures that the compound reaches the systemic circulation, where it can exert its therapeutic effects on the respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 55741-01-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,7,4 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 55741-01:
(7*5)+(6*5)+(5*7)+(4*4)+(3*1)+(2*0)+(1*1)=120
120 % 10 = 0
So 55741-01-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO2/c1-11(2)7-8-5-3-4-6-9(8)10(12)13/h3-6H,7H2,1-2H3,(H,12,13)
55741-01-0Relevant academic research and scientific papers
Directing group-controlled regioselectivity in an enzymatic C-H bond oxygenation
Negretti, Solymar,Narayan, Alison R. H.,Chiou, Karoline C.,Kells, Petrea M.,Stachowski, Jessica L.,Hansen, Douglas A.,Podust, Larissa M.,Montgomery, John,Sherman, David H.
supporting information, p. 4901 - 4904 (2014/04/17)
Highly regioselective remote hydroxylation of a natural product scaffold is demonstrated by exploiting the anchoring mechanism of the biosynthetic P450 monooxygenase PikCD50N-RhFRED. Previous studies have revealed structural and biochemical evidence for the role of a salt bridge between the desosamine N,N-dimethylamino functionality of the natural substrate YC-17 and carboxylate residues within the active site of the enzyme, and selectivity in subsequent C-H bond functionalization. In the present study, a substrate-engineering approach was conducted that involves replacing desosamine with varied synthetic N,N-dimethylamino anchoring groups. We then determined their ability to mediate enzymatic total turnover numbers approaching or exceeding that of the natural sugar, while enabling ready introduction and removal of these amino anchoring groups from the substrate. The data establish that the size, stereochemistry, and rigidity of the anchoring group influence the regioselectivity of enzymatic hydroxylation. The natural anchoring group desosamine affords a 1:1 mixture of regioisomers, while synthetic anchors shift YC-17 analogue C-10/C-12 hydroxylation from 20:1 to 1:4. The work demonstrates the utility of substrate engineering as an orthogonal approach to protein engineering for modulation of regioselective C-H functionalization in biocatalysis.
