7115-89-1

Basic information

• Product Name: 2-(Bromomethyl)benzoic acid
• Synonyms: 2-BROMOMETHYL-1-BENZOIC ACID;ART-CHEM-BB B019566;RARECHEM AL BO 0035;2-Bromomethyl-benzoic acid ,97%;2-Bromomethylbenzoic acid;2-(Bromomethyl)benzoic acid;2-(Bromomethyl)benzo;2-(broMoMethyl)pyridine-3-carboxylic acid
• CAS NO: 7115-89-1
• Molecular Formula: C₈H₇BrO₂
• Molecular Weight: 215.04
• Product Categories: Carboxylic Acids;Phenyls & Phenyl-Het;Carboxylic Acids;Phenyls & Phenyl-Het
• Mol File: 7115-89-1.mol
• Article Data: 11

Chemical Properties

• Melting Point: 148-151°C
• Boiling Point: 317.1°Cat760mmHg
• Flash Point: 145.6°C
• Appearance: /
• Density: 1.635g/cm³
• Vapor Pressure: 0.000165mmHg at 25°C
• Refractive Index: 1.614
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.66±0.36(Predicted)
• Water Solubility: Insoluble in water.
• CAS DataBase Reference: 2-(Bromomethyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Bromomethyl)benzoic acid(7115-89-1)
• EPA Substance Registry System: 2-(Bromomethyl)benzoic acid(7115-89-1)

Safety Data

• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN3261
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 7115-89-1(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

2-(Bromomethyl)benzoic acid contains bi functional groups such as benzylic bromide and carboxylic acid are involved in nucleophilic reactions and esterification reactions respectively.

InChI:InChI=1/C8H7BrO2/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4H,5H2,(H,10,11)

Upstream product

• 118-90-1 ortho-methylbenzoic acid 
• 128-08-5 N-Bromosuccinimide 
• 40819-28-1 2-(bromomethyl)benzoyl bromide 
• 87-41-2 2-benzofuran-1(3H)-one 

Downstream Products

• 2417-73-4 methyl 2-bromomethylbenzoate 
• 87-41-2 2-benzofuran-1(3H)-one 
• 612-20-4 2-(hydroxymethyl)benzoic acid 
• 7115-90-4 α-Bromo-o-toluyl Chloride 
• 105340-30-5 2-(bromomethyl)benzoic acid t-butyl ester 
• 328936-93-2 2-((2S,3R,4S,5R,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-2-ethylsulfanyl-tetrahydro-pyran-3-yloxymethyl)-benzoic acid 
• 328937-01-5 C₅₆H₅₈O₁₂ 
• 328936-98-7 2-((2S,3R,4S,5R,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-2-ethylsulfanyl-tetrahydro-pyran-3-yloxymethyl)-benzoic acid (2S,3R,4S,5R,6R)-3-benzyloxy-6-benzyloxymethyl-5-hydroxy-2-methoxy-tetrahydro-pyran-4-yl ester 
• 7115-93-7 2-aminooxymethyl-benzoic acid 
• 7116-02-1 2-Aminooxymethyl-benzoesaeureaethylester 
• 7115-92-6 2-Aethoxycarbonylaminooxymethyl-benzoesaeureaethylester 
• 7115-91-5 2-ethoxycarbonylbenzyl bromide 
• 55741-01-0 o-N,N-dimethylaminomethylbenzoic acid 
• 1583315-19-8 ((3R,4S,5S,7R,11R,12R,E)-12-ethyl-3,5,7,11-tetramethyl-2,8-dioxo-1-oxacyclododec-9-en-4-yl) 2-((dimethylamino)methyl)benzoate 

Relevant articles and documents

Synthesis of 2,3-dihydro-1H-2-benzazepin-1-ones and 3H-2-benzoxepin-1-ones by isocyanide-based multicomponent reaction/Wittig sequence starting from phosphonium salt precursors

A one-pot synthesis of multisubstituted 2,3-dihydro-1H-2-benzazepin-1-ones and 3H-2-benzoxepin-1-ones by an I-MCR/Wittig sequence was developed. The reaction of phosphonium salt 3, arylglyoxals 4, amine 5 (or without), and isocyanide 6 produced the 2,3-di

One-Pot Synthesis of 3-(1,2,3,4-Tetrahydroisoquinolin-1-yl)-isoquinolin-1(2 H)-ones by DEAD-Promoted Oxidative Ugi-Wittig -Reaction Starting from Phosphonium Salt Precursors

A new one-pot synthesis of 3-(1,2,3,4-tetrahydroisoquinolin-1-yl)-isoquinolin-1(2H)-ones by DEAD-promoted oxidative Ugi Wittig reaction was developed. The sequential reactions of (2-carboxybenzyl)triphenylphosphonium salts, isocyanides, and N-aryl-1,2,3,4

Phthalide: A direct building-block towards P,O and P,N hemilabile ligands. Application in the palladium-catalysed Suzuki-Miyaura cross-coupling of aryl chlorides

The direct synthesis of new hemilabile ligands from the economical, readily available lactone phthalide is described. Pd-complexes of one such ligand were found highly effective in general Suzuki-Miyaura cross-coupling reactions, including deactivated and hindered aryl chlorides. The Royal Society of Chemistry 2013.