2-Bromo-2-methylsuccinic acid, dimethyl ester

Base Information

• Chemical Name: 2-Bromo-2-methylsuccinic acid, dimethyl ester
• CAS No.: 29555-26-8
• Molecular Formula: C₇H₁₁BrO₄
• Molecular Weight: 239.066
• DSSTox Substance ID: DTXSID801270587
• Mol file: 29555-26-8.mol

Synonyms:DTXSID801270587;Dimethyl 2-bromo-2-methylsuccinate #;29555-26-8;1,4-Dimethyl 2-bromo-2-methylbutanedioate;2-Bromo-2-methylsuccinic acid, dimethyl ester

Chemical Property of 2-Bromo-2-methylsuccinic acid, dimethyl ester

Chemical Property:

• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 237.98407
• Heavy Atom Count: 12
• Complexity: 192

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(CC(=O)OC)(C(=O)OC)Br

Technology Process of 2-Bromo-2-methylsuccinic acid, dimethyl ester

There total 1 articles about 2-Bromo-2-methylsuccinic acid, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + ethanol (64-17-5) + 2-methylbutanedioic acid (498-21-5,636-60-2) → dimethyl 2-methyl-2-bromosuccinate (29555-26-8) + diethyl 2-bromo-2-methylsuccinate (29555-27-9) + 1-ethyl-4-methyl 2-bromo-2-methylsuccinate (149243-29-8) + 4-ethyl-1-methyl 2-bromo-2-methylsuccinate

Guidance literature:

With N-Bromosuccinimide; Perbenzoic acid; sulfuric acid; Yield given. Multistep reaction. Title compound not separated from byproducts; 1) 1,2-dichloroethane, reflux, 4 h, 2) CCl₄, reflux, overnight;

DOI:10.1002/oms.1210280315

upstream raw materials:

methanol

ethanol

2-methylbutanedioic acid