C₁₃H₁₀Cl₃NO

Base Information

• Chemical Name: C₁₃H₁₀Cl₃NO
• CAS No.: 1274694-43-7
• Molecular Formula: C₁₃H₁₀Cl₃NO
• Molecular Weight: 302.588
• Mol file: 1274694-43-7.mol

Synonyms:

Chemical Property of C₁₃H₁₀Cl₃NO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₁₀Cl₃NO

There total 5 articles about C₁₃H₁₀Cl₃NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,4'-trichloro-2'-nitrodiphenyl ether (2392-48-5) → C13H10Cl3NO (1274694-43-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogen / ethanol

2.1: tert.-butylnitrite; boron trifluoride diethyl etherate / tetrahydrofuran / 0 °C

2.3: 150 °C

3.1: lithium aluminium tetrahydride

With lithium aluminium tetrahydride; tert.-butylnitrite; boron trifluoride diethyl etherate; hydrogen; In tetrahydrofuran; ethanol; 2.2: |Sandmeyer Reaction / 2.3: |Rosenmund-van Braun Cyanation;

DOI:10.1016/j.bmcl.2012.12.022

Reference yield:

2,4-dichlorophenol (120-83-2,40477-79-0) → C13H10Cl3NO (1274694-43-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: potassium hydroxide / dimethyl sulfoxide / 100 °C

2.1: hydrogen / ethanol

3.1: tert.-butylnitrite; boron trifluoride diethyl etherate / tetrahydrofuran / 0 °C

3.3: 150 °C

4.1: lithium aluminium tetrahydride

With lithium aluminium tetrahydride; tert.-butylnitrite; boron trifluoride diethyl etherate; hydrogen; potassium hydroxide; In tetrahydrofuran; ethanol; dimethyl sulfoxide; 3.2: |Sandmeyer Reaction / 3.3: |Rosenmund-van Braun Cyanation;

DOI:10.1016/j.bmcl.2012.12.022

Reference yield:

5-Chloro-2-(2',4'-dichlorophenoxy)aniline (56966-52-0) → C13H10Cl3NO (1274694-43-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tert.-butylnitrite; boron trifluoride diethyl etherate / tetrahydrofuran / 0 °C

1.3: 150 °C

2.1: lithium aluminium tetrahydride

With lithium aluminium tetrahydride; tert.-butylnitrite; boron trifluoride diethyl etherate; In tetrahydrofuran; 1.2: |Sandmeyer Reaction / 1.3: |Rosenmund-van Braun Cyanation;

DOI:10.1016/j.bmcl.2012.12.022

upstream raw materials:

2,5-dichloronitrobenzene

2,4,4'-trichloro-2'-nitrodiphenyl ether

2,4-dichlorophenol

5-Chloro-2-(2',4'-dichlorophenoxy)aniline