sodium 6,8-disulfanyloctanoate

Base Information

• Chemical Name: sodium 6,8-disulfanyloctanoate
• CAS No.: 36915-02-3
• Molecular Formula: C8H16 O2 S2 . Na
• Molecular Weight: 230.3233
• Mol file: 36915-02-3.mol

Synonyms:Octanoic acid, 6,8-dimercapto-, monosodium salt (9CI);Sodium dihydrolipoate

Chemical Property of sodium 6,8-disulfanyloctanoate

Chemical Property:

• Vapor Pressure: 3.47E-06mmHg at 25°C
• Boiling Point: 360.8°C at 760 mmHg
• Flash Point: 172°C

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of sodium 6,8-disulfanyloctanoate

There total 2 articles about sodium 6,8-disulfanyloctanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Thioctic acid (1077-28-7,62-46-4) → dihydrothioctic acid sodium salt (36915-02-3)

Guidance literature:

Thioctic acid; With sodium hydroxide; In water; at 20 - 25 ℃; Large scale reaction;

With sodium tetrahydroborate; In water; at 40 - 60 ℃; for 2h;

DOI:10.1021/op200091t

Reference yield:

dihydrolipoic acid (462-20-4) → dihydrothioctic acid sodium salt (36915-02-3)

Guidance literature:

With sodium carbonate; In water;

DOI:10.1016/j.cattod.2014.05.038

Reference yield:

dihydrothioctic acid sodium salt (36915-02-3) + benzyl bromide (100-39-0) → (+/-)6,8-bis-thiobenzyl octanoic acid (95809-78-2)

Guidance literature:

dihydrothioctic acid sodium salt; benzyl bromide; With sodium hydroxide; In water; at 20 ℃; for 2h; Large scale reaction;

With hydrogenchloride; In water; ethyl acetate; pH=2;

DOI:10.1021/op200091t

upstream raw materials:

Thioctic acid

dihydrolipoic acid

Downstream raw materials:

(+/-)6,8-bis-thiobenzyl octanoic acid

Refernces

• 1、 -. "Method for synthesizing and preparing anti-tumor innovative drug, namely Devimistat". Paragraph 0023; 0026-0037. . Retrieved 2020/07/15.
• 2、 Paganelli,Piccolo,Pontini,Tassini,Rathod. "Aqueous-phase hydrogenation and hydroformylation reactions catalyzed by a new water-soluble [rhodium]-thioligand complex". . p. 64 - 69. Retrieved 2015/03/30.