alpha-(3,4-Dimethoxyphenyl)-beta-oxobenzenebutanamide

Base Information

Chemical Name:alpha-(3,4-Dimethoxyphenyl)-beta-oxobenzenebutanamide
CAS No.:93081-16-4
Molecular Formula:C₁₈H₁₉NO₄
Molecular Weight:313.353
Hs Code.:
DSSTox Substance ID:DTXSID601248906

Synonyms:alpha-(3,4-Dimethoxyphenyl)-beta-oxobenzenebutanamide;DTXSID601248906;93081-16-4

Suppliers and Price of alpha-(3,4-Dimethoxyphenyl)-beta-oxobenzenebutanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of alpha-(3,4-Dimethoxyphenyl)-beta-oxobenzenebutanamide

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:313.13140809
Heavy Atom Count:23
Complexity:406

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C(C(=O)CC2=CC=CC=C2)C(=O)N)OC

Technology Process of alpha-(3,4-Dimethoxyphenyl)-beta-oxobenzenebutanamide

There total 3 articles about alpha-(3,4-Dimethoxyphenyl)-beta-oxobenzenebutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57543-01-8
α-phenacetyl-3,4-dimethoxyphenylacetonitrile

: 93081-16-4
2-(3,4-dimethoxyphenyl)-3-oxo-4-phenylbutyramide

Guidance literature:: With hydrogenchloride; In water; acetic acid; Yield given; 1)35 - 50 deg C 2)room temp., 48h;
DOI:10.1135/cccc19841002

Reference yield:

: 103-82-2
phenylacetic acid

: 93081-16-4
2-(3,4-dimethoxyphenyl)-3-oxo-4-phenylbutyramide

Guidance literature:: Multi-step reaction with 2 steps

1: NaOEt / ethanol / 1)reflux 3.5h 2)stand overnight

2: HCl / acetic acid; H₂O / 1)35 - 50 deg C 2)room temp., 48h

With hydrogenchloride; sodium ethanolate; In ethanol; water; acetic acid;
DOI:10.1135/cccc19841002

Reference yield:

: 93-17-4
3,4-dimethoxyphenylacetonitrile

: 93081-16-4
2-(3,4-dimethoxyphenyl)-3-oxo-4-phenylbutyramide

Guidance literature:: Multi-step reaction with 2 steps

1: NaOEt / ethanol / 1)reflux 3.5h 2)stand overnight

2: HCl / acetic acid; H₂O / 1)35 - 50 deg C 2)room temp., 48h

With hydrogenchloride; sodium ethanolate; In ethanol; water; acetic acid;
DOI:10.1135/cccc19841002