57543-01-8

Upstream product

• 103-82-2 phenylacetic acid 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 
• 101-97-3 Ethyl 2-phenylethanoate 

Downstream Products

• 93081-16-4 2-(3,4-dimethoxyphenyl)-3-oxo-4-phenylbutyramide 
• 332351-96-9 1-benzyl-3-phenyl-5-(3-pyridyl)-7,8-dimethoxypyrazolo[3,4-c]isoquinoline 
• 57543-03-0 1-(3,4-dimethoxyphenyl)-3-phenyl-propan-2-amine 
• 57543-04-1 N-[1-benzyl-2-(3,4-dimethoxyphenyl)ethyl]formamide 
• 93081-20-0 1-(3,4-dimethoxyphenyl)-3-phenylpropan-2-ol 
• 93081-21-1 1-(3,4-dimethoxyphenyl)-3-phenyl-2-propyl chloride 
• 93081-23-3 N-methyl-1-(3,4-dimethoxyphenyl)-3-phenyl-2-propylamine 
• 118673-86-2 1-<1-(3,4-dimethoxyphenyl)-3-phenyl-2-propyl>-4-methylpiperazine 
• 57543-02-9 1-(3,4-dimethoxyphenyl)-3-phenyl-propan-2-one 
• 351018-34-3 1-phenyl-3-benzyl-4-(3,4-dimethoxyphenyl)-5-aminopyrazole 

Relevant academic research and scientific papers

Oxidative aromatic C-O bond formation: synthesis of 3-functionalized benzo[b]furans by FeCl3-mediated ring closure of a-Aryl ketones

A variety of 3-functionalized benzo[b]furans were achieved by way of a FeCl3-medlated Intramolecular cyclization of electron-rich a-aryl ketones. The alkoxy substituent on the benzene ring In the substrates was essential for an efficient cyclization to occur. This novel method allows the construction of benzo[b]furan rings by joining the O-atom on the side chain to the benzene ring via direct oxidative aromatic C-O bond formation.

A versatile synthesis of pyrazolo[3,4-c]isoquinoline derivatives by reaction of 4-aryl-5-aminopyrazoles with aryl/heteroaryl aldehydes: The effect of the heterocycle on the reaction pathways

The reaction of 4-(3,4-dimethoxyphenyl)-5-aminopyrazoles 7A-D with aromatic and heterocyclic aldehydes in strong acidic media (trifluoroacetic or formic acid) has been studied. The initial azomethine derivatives 8 undergo cyclization similar to the Pictet

New structural analogs of papaverine: 3 benzyl 6,7 dimethoxy (di and tetrahydro) isoquinolines

Syntheses of 3 benzyl 3,4 dihydroisoquinolines by cyclisation of a N acyl α benzylhomoveratrylamine by means of polyphosphoric acid ester, in boiling toluene, gave yields between 60 and 90%. While the hydrogenation of these dihydroisoquinolines to tetrahydroisoquinolines with an alkaline borohydride gave satisfactory result, their dehydrogenation into isoquinolines could not be accomplished. Pharmacological properties of the hydrobromides or hydrochlorides of the bases of the two series of the aforementioned 3 benzylisoquinolines and comparison of their activities with those of papaverine and the analogues 1 and 4 benzylisoquinolines are reported.