8H-Imidazo[4,5-g]quinazolin-8-one, 3,5-dihydro-3-methyl-

Base Information

• Chemical Name: 8H-Imidazo[4,5-g]quinazolin-8-one, 3,5-dihydro-3-methyl-
• CAS No.: 105664-87-7
• Molecular Formula: C10H8N4O
• Molecular Weight: 200.2
• Mol file: 105664-87-7.mol

Synonyms:

Chemical Property of 8H-Imidazo[4,5-g]quinazolin-8-one, 3,5-dihydro-3-methyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8H-Imidazo[4,5-g]quinazolin-8-one, 3,5-dihydro-3-methyl-

There total 1 articles about 8H-Imidazo[4,5-g]quinazolin-8-one, 3,5-dihydro-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-chloro-6-nitro-4(3H)-quinazolinone (53449-14-2) → 3-methyl-3H-imidazo<4,5-g>quinazoline-8(7H)-one (105664-87-7)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂O / 15 h / 110 - 120 °C

2: 53 percent / H₂, 1 N KOH / Pd/C / 15 h / 2585.7 Torr

3: 63 percent / acetic anhydride / 24 h / Heating

With potassium hydroxide; hydrogen; acetic anhydride; palladium on activated charcoal; In water;

DOI:10.1021/jo00375a007

Reference yield:

3-methyl-3H-imidazo<4,5-g>quinazoline-8(7H)-one (105664-87-7) → BPIQ-1 (174709-30-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 88 percent / P₂S₅, pyridine / 16 h / Heating

2: 82 percent / KOH / methanol; H₂O / 16 h / 20 °C

3: 52 percent / 3-bromoaniline hydrochloride / propan-2-ol / 1 h / Heating

With pyridine; potassium hydroxide; tetraphosphorus decasulfide; m-bromoaniline hydrochloride; In methanol; water; isopropyl alcohol;

DOI:10.1021/jm950692f

upstream raw materials:

7-chloro-6-nitro-4(3H)-quinazolinone

Downstream raw materials:

BPIQ-1

Refernces