Benzoic acid, 3,4,5-trimethoxy-, 2-(4-(3-dibenzo(b,e)thiepin-11(6H)-ylidenepropyl)-1-piperazinyl)ethyl ester, (E)-, (Z)-2-butenedioate (1:2)

Base Information

• Chemical Name: Benzoic acid, 3,4,5-trimethoxy-, 2-(4-(3-dibenzo(b,e)thiepin-11(6H)-ylidenepropyl)-1-piperazinyl)ethyl ester, (E)-, (Z)-2-butenedioate (1:2)
• CAS No.: 93665-40-8
• Molecular Formula: 2C₄H₄O₄*C₃₃H₃₈N₂O₅S
• Molecular Weight: 806.888
• Mol file: 93665-40-8.mol

Synonyms:

Chemical Property of Benzoic acid, 3,4,5-trimethoxy-, 2-(4-(3-dibenzo(b,e)thiepin-11(6H)-ylidenepropyl)-1-piperazinyl)ethyl ester, (E)-, (Z)-2-butenedioate (1:2)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 3,4,5-trimethoxy-, 2-(4-(3-dibenzo(b,e)thiepin-11(6H)-ylidenepropyl)-1-piperazinyl)ethyl ester, (E)-, (Z)-2-butenedioate (1:2)

There total 3 articles about Benzoic acid, 3,4,5-trimethoxy-, 2-(4-(3-dibenzo(b,e)thiepin-11(6H)-ylidenepropyl)-1-piperazinyl)ethyl ester, (E)-, (Z)-2-butenedioate (1:2) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3,4,5-Trimethoxybenzoyl chloride (4521-61-3) + maleic acid (110-16-7,26099-09-2) + (E)-1-<3-(6,11-dihydrodibenzothiepin-11-ylidene)propyl>-4-(2-hydroxyethyl)piperazine (93665-28-2,1839-28-7) → (E)-1-<3-(6,11-dihydrodibenzothiepin-11-ylidene)propyl>-4-<2-(3,4,5-trimethoxybenzoyloxy)ethyl>piperazine bis(hydrogen maleate) (93665-40-8)

Guidance literature:

In ethanol; chloroform; benzene; for 36h; Ambient temperature;

DOI:10.1135/cccc19841816

Reference yield:

1-(2-hydroxyethyl)piperazine (103-76-4) → (E)-1-<3-(6,11-dihydrodibenzothiepin-11-ylidene)propyl>-4-<2-(3,4,5-trimethoxybenzoyloxy)ethyl>piperazine bis(hydrogen maleate) (93665-40-8)

Guidance literature:

Multi-step reaction with 2 steps

1: CHCl₃ / 3 h / Heating

2: 90 percent / benzene; CHCl₃; ethanol / 36 h / Ambient temperature

In ethanol; chloroform; benzene;

DOI:10.1135/cccc19841816

Reference yield:

11-(3-Bromopropylidene)-6,11-dihydrodibenz[b,e]thiepine (73149-95-8) → (E)-1-<3-(6,11-dihydrodibenzothiepin-11-ylidene)propyl>-4-<2-(3,4,5-trimethoxybenzoyloxy)ethyl>piperazine bis(hydrogen maleate) (93665-40-8)

Guidance literature:

Multi-step reaction with 2 steps

1: CHCl₃ / 3 h / Heating

2: 90 percent / benzene; CHCl₃; ethanol / 36 h / Ambient temperature

In ethanol; chloroform; benzene;

DOI:10.1135/cccc19841816

upstream raw materials:

3,4,5-Trimethoxybenzoyl chloride

maleic acid

(E)-1-<3-(6,11-dihydrodibenzothiepin-11-ylidene)propyl>-4-(2-hydroxyethyl)piperazine

1-(2-hydroxyethyl)piperazine