(S)-1-Phenyl-2,2-difluoroethanol

Base Information

Chemical Name:(S)-1-Phenyl-2,2-difluoroethanol
CAS No.:123986-75-4
Molecular Formula:C₈H₈F₂O
Molecular Weight:158.148
Hs Code.:
European Community (EC) Number:870-874-3
Nikkaji Number:J1.255.155J

Synonyms:123986-75-4;(1S)-2,2-difluoro-1-phenylethan-1-ol;(S)-1-Phenyl-2,2-difluoroethanol;(1S)-2,2-difluoro-1-phenylethanol;SCHEMBL10605435;XOYZGEQHDLLDHZ-ZETCQYMHSA-N;(S)-2,2-difluoro-1-phenylethanol;AT21495;CS-0239865;(S)-2,2-DIFLUORO-1-PHENYLETHAN-1-OL;EN300-220212

Suppliers and Price of (S)-1-Phenyl-2,2-difluoroethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (S)-1-Phenyl-2,2-difluoroethanol

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:158.05432120
Heavy Atom Count:11
Complexity:111

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C(F)F)O
Isomeric SMILES:C1=CC=C(C=C1)[C@@H](C(F)F)O

Technology Process of (S)-1-Phenyl-2,2-difluoroethanol

There total 41 articles about (S)-1-Phenyl-2,2-difluoroethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 868761-04-0
2,2-difluoro-1-phenyl-2-(phenylselanyl)ethanol

: 82255-42-3,123986-75-4,145373-94-0,345-64-2
2,2-difluoro-1-phenyl-ethanol

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 100 ℃; for 0.5h;
DOI:10.1039/b603041f

Reference yield: 99.0%

: 395-01-7
2,2-difluoro-1-phenylethanone

: 82255-42-3,123986-75-4,145373-94-0,345-64-2
2,2-difluoro-1-phenyl-ethanol

Guidance literature:: With C₃₆H₄₆Cl₄N₄Ru₂; isopropyl alcohol; sodium hydroxide; at 40 - 80 ℃; for 2h; Reagent/catalyst; Catalytic behavior; Inert atmosphere;
DOI:10.1039/c7nj02822a

Reference yield: 95.0%

: 450-95-3
2-fluoroacetophenone

: 123986-75-4,345-64-2,82255-42-3,145373-94-0
(S)-2,2-difluoro-1-phenylethan-1-ol

Guidance literature:: With B enzyme from Geotrichum candidum IFO 4597; D-glucose-6-phosphate dehydrogenase; NADPH; at 30 ℃; for 20h; pH=7.0; Enzymatic reaction;
DOI:10.1021/jo991283k