1-{[4-(Trifluoromethyl)phenyl]methyl}-1,3-dihydro-2H-imidazole-2-thione

Base Information

Chemical Name:1-{[4-(Trifluoromethyl)phenyl]methyl}-1,3-dihydro-2H-imidazole-2-thione
CAS No.:105763-99-3
Molecular Formula:C₁₁H₉F₃N₂S
Molecular Weight:258.267
Hs Code.:
ChEMBL ID:CHEMBL64938
DSSTox Substance ID:DTXSID80561861
Nikkaji Number:J271.803K
Wikidata:Q82445764
Mol file:105763-99-3.mol

Synonyms:CHEMBL64938;105763-99-3;DTXSID80561861;BDBM50406075;1-{[4-(Trifluoromethyl)phenyl]methyl}-1,3-dihydro-2H-imidazole-2-thione;AKOS012176911

Suppliers and Price of 1-{[4-(Trifluoromethyl)phenyl]methyl}-1,3-dihydro-2H-imidazole-2-thione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-{[4-(Trifluoromethyl)phenyl]methyl}-1,3-dihydro-2H-imidazole-2-thione

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:258.04385396
Heavy Atom Count:17
Complexity:319

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CN2C=CNC2=S)C(F)(F)F

Technology Process of 1-{[4-(Trifluoromethyl)phenyl]methyl}-1,3-dihydro-2H-imidazole-2-thione

There total 3 articles about 1-{[4-(Trifluoromethyl)phenyl]methyl}-1,3-dihydro-2H-imidazole-2-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 105763-99-3
1-(4-Trifluoromethyl-benzyl)-1,3-dihydro-imidazole-2-thione

Guidance literature:: Multi-step reaction with 3 steps

1: 0.33 h / Heating

2: sodium borohydride / ethanol / 24 h / Ambient temperature

3: 12 N HCl / ethanol; H₂O / 2 h / Heating

With hydrogenchloride; sodium tetrahydroborate; In ethanol; water;
DOI:10.1021/jm00386a008

Reference yield:

: (2,2-Dimethoxy-ethyl)-[1-(4-trifluoromethyl-phenyl)-meth-(E)-ylidene]-amine

: 105763-99-3
1-(4-Trifluoromethyl-benzyl)-1,3-dihydro-imidazole-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: sodium borohydride / ethanol / 24 h / Ambient temperature

2: 12 N HCl / ethanol; H₂O / 2 h / Heating

With hydrogenchloride; sodium tetrahydroborate; In ethanol; water;
DOI:10.1021/jm00386a008