C₁₂H₁₄O₅

Base Information

• Chemical Name: C₁₂H₁₄O₅
• CAS No.: 34276-42-1
• Molecular Formula: C₁₂H₁₄O₅
• Molecular Weight: 238.24
• Mol file: 34276-42-1.mol

Synonyms:

Chemical Property of C₁₂H₁₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₁₄O₅

There total 4 articles about C₁₂H₁₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + ethyl 2-hydroxy-3-(4-methoxyphenyl)propanoate (38618-53-0) → (R)-2-hydroxy-3-(4-methoxyphenyl)propanoic acid (1206734-18-0) + C12H14O5 (34276-42-1) + (S)-2-hydroxy-3-(4-methoxyphenyl)propanoic acid (33173-34-1)

Guidance literature:

vinyl acetate; ethyl 2-hydroxy-3-(4-methoxyphenyl)propanoate; With Pseudomonas cepacia lipase; In tert-butyl methyl ether; at 20 ℃; for 240h; Enzymatic reaction;

With sodium phosphate dibasic dihydrate; water; sodium chloride; sodium hydroxide; bovine α-chymotrypsin; for 72h; pH=7.8; optical yield given as %ee; stereoselective reaction; Further stages; Enzymatic reaction;

DOI:10.1016/j.tetasy.2009.10.013

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + ethyl 2-hydroxy-3-(4-methoxyphenyl)propanoate (38618-53-0) → (R)-2-hydroxy-3-(4-methoxyphenyl)propanoic acid (1206734-18-0) + ethyl (S)-2-hydroxy-3-(4-methoxyphenyl)propanoate (1206734-19-1) + ethyl (R)-2-hydroxy-3-(4-methoxyphenyl)propanoate (33173-51-2) + C12H14O5 (34276-42-1) + ethyl (S)-2-acetoxy-3-(4-methoxyphenyl)propanoate (37504-76-0)

Guidance literature:

vinyl acetate; ethyl 2-hydroxy-3-(4-methoxyphenyl)propanoate; With Pseudomonas cepacia lipase; In tert-butyl methyl ether; at 20 ℃; for 240h; Enzymatic reaction;

With sodium phosphate dibasic dihydrate; water; sodium chloride; sodium hydroxide; bovine α-chymotrypsin; for 72h; pH=7.8; Enzymatic reaction;

With hydrogenchloride; In water; pH=2 - 3; optical yield given as %ee; stereoselective reaction;

DOI:10.1016/j.tetasy.2009.10.013

Reference yield:

ethyl 2-acetoxy-3-(4-methoxyphenyl)propanoate (125986-63-2) → C12H14O5 (34276-42-1) + C12H14O5 + ethyl (R)-2-acetoxy-3-(4-methoxyphenyl)propanoate (33173-52-3) + ethyl (S)-2-acetoxy-3-(4-methoxyphenyl)propanoate (37504-76-0)

Guidance literature:

ethyl 2-acetoxy-3-(4-methoxyphenyl)propanoate; With sodium phosphate dibasic dihydrate; water; sodium chloride; sodium hydroxide; bovine α-chymotrypsin; for 96h; pH=7.8; Enzymatic reaction;

With hydrogenchloride; In water; pH=2 - 3; optical yield given as %ee; stereoselective reaction;

DOI:10.1016/j.tetasy.2009.10.013

upstream raw materials:

vinyl acetate

ethyl 2-hydroxy-3-(4-methoxyphenyl)propanoate

ethyl 2-acetoxy-3-(4-methoxyphenyl)propanoate