({2-[2-(2-Chloroethoxy)ethoxy]ethoxy}methyl)benzene

Base Information

• Chemical Name: ({2-[2-(2-Chloroethoxy)ethoxy]ethoxy}methyl)benzene
• CAS No.: 105891-50-7
• Molecular Formula: C13H19ClO3
• Molecular Weight: 258.745
• DSSTox Substance ID: DTXSID10543655
• Nikkaji Number: J1.245.500C
• Wikidata: Q82420593
• Mol file: 105891-50-7.mol

Synonyms:105891-50-7;Benzene, [[2-[2-(2-chloroethoxy)ethoxy]ethoxy]methyl]-;SCHEMBL6267162;DTXSID10543655;({2-[2-(2-CHLOROETHOXY)ETHOXY]ETHOXY}METHYL)BENZENE

Chemical Property of ({2-[2-(2-Chloroethoxy)ethoxy]ethoxy}methyl)benzene

Chemical Property:

• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 10
• Exact Mass: 258.1022722
• Heavy Atom Count: 17
• Complexity: 161

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COCCOCCOCCCl

Technology Process of ({2-[2-(2-Chloroethoxy)ethoxy]ethoxy}methyl)benzene

There total 6 articles about ({2-[2-(2-Chloroethoxy)ethoxy]ethoxy}methyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

triethylene glycol monobenzyl ether (55489-58-2,1201808-31-2) → 1-chloro-10-phenyl-3,6,9-trioxadecane (105891-50-7)

Guidance literature:

With pyridine; thionyl chloride; at 65 ℃; for 4h; Inert atmosphere;

DOI:10.1039/b818606e

Reference yield: 98.0%

2-[2-(chloroethoxy)ethoxy]ethanol (5197-62-6) + benzyl bromide (100-39-0) → 1-chloro-10-phenyl-3,6,9-trioxadecane (105891-50-7)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1002/(SICI)1521-3765(20000103)6:1<111::AID-CHEM111>3.0.CO;2-X

Reference yield: 64.9%

triethylene glycol monobenzyl ether (55489-58-2,1201808-31-2) + p-toluenesulfonyl chloride (98-59-9) → triethylene glycol monobenzyl tosyl ether (84131-04-4) + 1-chloro-10-phenyl-3,6,9-trioxadecane (105891-50-7)

Guidance literature:

triethylene glycol monobenzyl ether; p-toluenesulfonyl chloride; In pyridine; at 0 - 20 ℃; for 17.5h;

With water; In pyridine; ethyl acetate; Product distribution / selectivity;

upstream raw materials:

triethylene glycol monobenzyl ether

2-[2-(chloroethoxy)ethoxy]ethanol

benzyl bromide

benzyl chloride

Downstream raw materials:

1,21-diphenyl-2,5,8,11,14,17,20-heptaoxahenicosane

1-((2-(2-(2-(2-(2-(2-(2-(benzyloxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)methyl)benzene

(2-{2-[2-(2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptyloxy)-ethoxy]-ethoxy}-ethoxymethyl)-benzene

((2-(2-(2-azidoethoxy)ethoxy)ethoxy)methyl)benzene