4-(Dimethylamino)-3-isopropylphenol

Base Information

• Chemical Name: 4-(Dimethylamino)-3-isopropylphenol
• CAS No.: 14200-18-1
• Molecular Formula: C₁₁H₁₇NO
• Molecular Weight: 179.262
• European Community (EC) Number: 660-878-1
• Mol file: 14200-18-1.mol

Synonyms:4-(Dimethylamino)-3-isopropylphenol;AKOS024324695

Chemical Property of 4-(Dimethylamino)-3-isopropylphenol

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 179.131014166
• Heavy Atom Count: 13
• Complexity: 156

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)C1=C(C=CC(=C1)O)N(C)C

Technology Process of 4-(Dimethylamino)-3-isopropylphenol

There total 3 articles about 4-(Dimethylamino)-3-isopropylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(1-methylethyl)-4-aminophenol (82774-61-6) + methyl iodide (74-88-4) → 4-Dimethylamino-3-isopropyl-phenol (14200-18-1)

Guidance literature:

With ethanol; sodium carbonate; Erhitzen des Reaktionsprodukts unter 10 Torr bis auf 250grad;

DOI:10.1021/ja01846a078

Reference yield:

di-isopropyl ether (108-20-3) + 4-(N,N-dimethylamino)phenol (619-60-3) → 4-Dimethylamino-3-isopropyl-phenol (14200-18-1) + 4-Dimethylamino-2-isopropyl-phenol

Guidance literature:

With hydrogen fluoride;

DOI:10.1021/ja01874a007

Reference yield:

→ 4-Dimethylamino-3-isopropyl-phenol (14200-18-1)

Guidance literature:

1.) 4-Amino-3-isopropyl-phenol, Methyljodid, Na2CO3, A., Δ, 2.) 270-320gradC;

upstream raw materials:

di-isopropyl ether

4-(N,N-dimethylamino)phenol

3-(1-methylethyl)-4-aminophenol

methyl iodide

Downstream raw materials:

methyl-carbamic acid-(4-dimethylamino-3-isopropyl-phenyl ester)

4-dimethylcarbamoyloxy-2-isopropyl-tri-N-methyl-anilinium; iodide

2-isopropyl-tri-N-methyl-4-methylcarbamoyloxy-anilinium; iodide